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- info - Home https://psychonautwiki.org/wiki/File:Behandeling-4-fa-intoxicatie.pdf https://psychonautwiki.org/wiki/File:4-FA%20risicobeoordeling%20(2016)21 KB (3,439 words) - 15:42, 30 July 2022
- been characterized as a potent D2 dopamine agonist but not a dopamine reuptake inhibitor in humans. This D2 dopamine agonism contributes to the infamous25 KB (3,130 words) - 14:33, 16 April 2024
- species and autoxidation of dopamine. In rodents and primates, sufficiently high doses of amphetamine causes damage to dopamine neurons, characterized as41 KB (5,610 words) - 19:01, 7 April 2024
- In order to maintain consistency across the wiki, images of molecular structures should be produced in a standardized format rather than obtained from19 KB (857 words) - 09:55, 15 September 2022
- other MAOIs, stimulants and certain substances which release serotonin or dopamine. It is recommended to avoid blends or branded products if the active psychoactive19 KB (2,209 words) - 23:08, 21 April 2024
- 1371/journal.pone.0194984. ISSN 1932-6203. 3-MeO-PCE (TripSit) | https://wiki.tripsit.me/wiki/3-MeO-PCE https://www.zakonyprolidi.cz/cs/2013-463?text=o+seznam20 KB (2,787 words) - 17:34, 17 March 2024
- to excessive pre-synaptic dopamine autoxidation, a mechanism of neurotoxicity. Similar to the neurotoxic effects on the dopamine system, methamphetamine41 KB (5,798 words) - 13:29, 16 April 2024
- the wiki. For example adding two brackets around a term like "serotonergic psychedelic" (serotonergic psychedelic) will link to the PsychonautWiki page10 KB (1,405 words) - 18:40, 20 August 2020
- Main Page (section Please don't crawl the wiki. Use our API instead.PsychonautWiki ❤️ Developers. Please report any obstacles.)pyrrolidine ⋅ Tropane alkaloid ⋅ Tryptamine Acetylcholine ⋅ Adrenaline ⋅ Dopamine ⋅ GABA ⋅ Glutamate ⋅ Hormone ⋅ Melatonin ⋅ Neuron ⋅ Neurotransmitter ⋅21 KB (1,004 words) - 23:38, 13 May 2024
- (PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M18 KB (2,543 words) - 21:36, 21 July 2022
- pharmacology, but it likely produces its effects by increasing levels of dopamine, norepinephrine, and serotonin in the brain. 4-FMA was first detected being21 KB (3,467 words) - 16:14, 30 July 2022
- ISSN 0378-4274. https://psychonautwiki.org/wiki/File:Nbome_death_news_i2013e0190_disp.jpg https://psychonautwiki.org/wiki/File:Nbome_death_news_i2013e0191_disp28 KB (4,417 words) - 14:00, 16 April 2024
- primarily as a potent norepinephrine-dopamine reuptake inhibitor. Reduced re-uptake of norepinephrine and dopamine results in higher concentrations of the23 KB (3,267 words) - 23:45, 21 April 2024
- and 6-APB. It produces its effects by promoting the release of serotonin, dopamine, and norepinephrine in the brain, particularly serotonin. MDMA was first85 KB (10,499 words) - 14:24, 16 April 2024
- stimulant effects. Responsible use Dopamine Substituted piperidine [Piperazine (Wikipedia)https://en.wikipedia.org/wiki/Piperazine] Substituted piperazine5 KB (298 words) - 10:10, 24 May 2022
- serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) with Ki values of 117, 150, and 2698 nM for the norepinephrine transporter (NET), dopamine transporter33 KB (4,870 words) - 14:34, 16 April 2024
- cognitive and memory impairment and amnesia. Some dissociatives affect the dopamine and/or opioid systems and are capable of inducing euphoria. Dissociatives12 KB (1,097 words) - 02:41, 12 May 2024
- prominent of which are increasing concentrations of the neurotransmitters dopamine and norepinephrine by either promoting release (e.g. amphetamine, methamphetamine)11 KB (1,055 words) - 02:52, 12 May 2024
- PCP-Thread-%28Part-1%29 3-MeO-PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential Morris, H., Wallach25 KB (3,520 words) - 21:44, 6 May 2024
- thought to work by increasing levels of certain neurotransmitters, such as dopamine, serotonin, and/or norepinephrine in certain regions in the brain. MAOIs9 KB (1,069 words) - 21:47, 13 May 2024
- experienced by users of 2C-B. Research also suggests that 2C-B increases dopamine levels in the brains of rats which may contribute to its psychoactivity36 KB (4,745 words) - 16:35, 7 April 2024
- primarily acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). It is most active at modulating levels of dopamine and, to a lesser extent, norepinephrine31 KB (4,254 words) - 15:15, 6 May 2024
- receptors with serotonin, dopamine, and norepinephrine. Activation of mu receptors allows for the disinhibition of serotonin and dopamine neurons by blocking19 KB (2,797 words) - 02:47, 12 May 2024
- and thus dopamine accumulates in the synaptic cleft. The increased concentration of dopamine in the synapse activates post-synaptic dopamine receptors47 KB (6,322 words) - 08:08, 3 May 2024
- reinforcing potential of mephedrone. Dopamine and serotonin were collected using microdialysis, and increases in dopamine and serotonin were measured. Mephedrone29 KB (3,963 words) - 14:23, 16 April 2024
- acts as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine and dopamine in the brain17 KB (2,934 words) - 17:24, 18 January 2024
- primarily as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine and dopamine neurotransmitters17 KB (3,024 words) - 17:25, 18 January 2024
- with MDMA, MDA is thought to act primarily as a serotonin-norepinephrine-dopamine reuptake inhibitor and releasing agent.[citation needed] However, MDA is31 KB (4,379 words) - 12:23, 6 May 2024
- monoamine chain can be found in many neurotransmitters, including histamine, dopamine, serotonin and noradrenaline. It is also found in many psychoactive substances5 KB (628 words) - 23:12, 21 April 2024
- such as dopamine, serotonin and noradrenaline. The agonism of this set of receptors results in the release of increased concentrations of dopamine, serotonin23 KB (3,617 words) - 09:16, 17 April 2024
- not reduced by the dopamine receptor antagonist haloperidol in rats. In addition, alpha-methyl-p-tyrosine, an inhibitor of dopamine synthesis, blocks the19 KB (3,104 words) - 11:29, 16 April 2024
- widely-prescribed ADHD medication methylphenidate. It is a norepinephrine-dopamine reuptake inhibitor (NDRI). Isopropylphenidate has been investigated for19 KB (2,684 words) - 18:04, 30 July 2022
- 1950s. It produces its activity by increasing the levels of serotonin, dopamine, and norepinephrine in the brain. The synthesis and pharmacology of 3-FPM15 KB (2,265 words) - 06:42, 8 September 2023
- of mephedrone (4-MMC). The mechanism of action is not fully studied, but dopamine and serotonin and norepinephrine releasing activity is known to be involved18 KB (2,590 words) - 21:20, 30 April 2024
- thought to act primarily as a dopamine and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of dopamine and norepinephrine neurotransmitters16 KB (2,465 words) - 15:45, 9 May 2024
- releasing agent of the main three monoamines; serotonin, norepinephrine, and dopamine, and as a non-selective serotonin receptor agonist. αMT's psychedelic effects25 KB (2,825 words) - 16:14, 28 November 2022
- potent dopamine releaser. This indicates that 3-FEA effectively increases the levels of all the three major monoamine neurotransmitters dopamine, norepinephrine19 KB (3,317 words) - 15:23, 30 July 2022
- profile of GHB. GHB's effect on dopamine release is biphasic. This means that while low concentrations stimulate dopamine release via the GHB receptor, higher35 KB (4,460 words) - 13:32, 16 April 2024
- the notable exception of 4-FA), it most likely acts primarily as both a dopamine and norepinephrine releasing agent, with modest selectivity for serotonin15 KB (2,726 words) - 11:39, 17 February 2024
- highly selective serotonin releasing agent (SSRA) with neglible effects on dopamine and norepinephrine. MDAI was developed by the American medicinal chemist17 KB (2,560 words) - 07:40, 12 October 2023
- known, but it is likely similar to that of LSD, which acts on serotonin, dopamine, and norepinephrine receptors in the brain. 1V-LSD is a research chemical28 KB (3,658 words) - 15:27, 10 March 2023
- both a dopamine reuptake inhibitor and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters18 KB (2,561 words) - 14:02, 16 April 2024
- includes compounds like MDPV, hexen, and a-PHP. It acts as a norepinephrine-dopamine reuptake inhibitor. α-PVP was patented in the 1960s by Boehringer Ingelheim24 KB (3,456 words) - 00:08, 3 November 2023
- acts as both a dopamine and norepinephrine releasing agent. This means it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters12 KB (1,928 words) - 23:42, 21 April 2024
- mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These neurotransmitters are thought to be responsible for regulating pleasure19 KB (2,841 words) - 14:21, 16 April 2024
- is as a D2 dopaminergic receptor antagonist. This means that it blocks dopamine from binding to the receptor, meanwhile not activating it.[citation needed]4 KB (510 words) - 11:41, 22 June 2023
- stimulants, increases dopamine levels in the brain which can lead to severe manic psychosis in the short-term in addition to persisting dopamine receptor down19 KB (2,776 words) - 00:39, 1 August 2022
- such as dopamine, serotonin and noradrenaline. The agonism of this set of receptors results in the release of increased concentrations of dopamine, serotonin19 KB (2,675 words) - 16:54, 31 March 2024
- effects of chronic memantine treatment. Memantine acts as an agonist at the dopamine D2 receptor with equal or slightly higher affinity than to the NMDA receptors17 KB (2,270 words) - 05:20, 1 May 2024
- sertraline has noticeable activity at the dopamine transporter protein and could be considered a serotonin-dopamine reuptake inhibitor. Several other SSRIs15 KB (1,687 words) - 18:59, 22 November 2023
- others. Hexedrone most likely acts as both a dopamine and norepinephrine reuptake inhibitor. This allows dopamine and norepinephrine to build up within the8 KB (961 words) - 23:45, 21 April 2024
- pronounced than other racetams. That may be due phenypiracetam's action as a dopamine reuptake inhibitor and noradrenaline reuptake inhibitor. Phenylpiracetam11 KB (1,273 words) - 00:25, 6 May 2024
- benzeneethanamine) is a trace amine and influencer of many neurotransmitters, such as dopamine and serotonin. Phenethylamine is an important molecule in the brain, but7 KB (919 words) - 17:25, 24 November 2023
- 2C-T-2 (category PsychonautWiki articles needing factual verification from October 2020)substances which promotes the release of neurotransmitters such as serotonin or dopamine. These substances include but are not limited to: In November 2003, the22 KB (2,627 words) - 23:08, 29 May 2021
- not reduced by the dopamine receptor antagonist haloperidol in rats. In addition, alpha-methyl-p-tyrosine, an inhibitor of dopamine synthesis, blocks the18 KB (3,163 words) - 18:25, 30 April 2024
- act primarily as a mild norepinephrine-dopamine reuptake inhibitor. Reduced re-uptake of norepinephrine and dopamine results in higher concentrations of the11 KB (1,751 words) - 20:42, 12 September 2022
- it most likely acts primarily as a triple releasing agent of serotonin, dopamine, and norepinephrine.[citation needed] Disclaimer: The effects listed below14 KB (2,687 words) - 15:28, 30 July 2022
- Neurotransmitter Monoamine Receptor Synapse Blood–brain barrier Serotonin Dopamine Glutamate NMDA AMPA Kainate receptor GABA Orexin Sigma receptor Adenosine599 bytes (162 words) - 23:00, 21 April 2024
- positions. 3,4-CTMP acts as a dopamine and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of dopamine and norepinephrine neurotransmitters24 KB (3,701 words) - 23:42, 21 April 2024
- and beta-2 adrenergic receptors. It also acts as a NDRA (norepinephrine-dopamine releasing agent). Ephedrine, a sympathomimetic amine, acts on part of the13 KB (1,767 words) - 16:46, 7 April 2024
- efficiency dopamine reuptake inhibitor than the closely related methylphenidate, meaning that it effectively boosts the levels of dopamine neurotransmitters17 KB (2,757 words) - 17:49, 30 July 2022
- 5-MAPB is a triple reuptake inhibitor for the monoamines norepinephrine, dopamine and serotonin as well as being an agonist for the 5-HT2A and 5-HT2B receptors13 KB (2,233 words) - 00:32, 31 December 2022
- produces its effects by increasing levels of serotonin, norepinephrine, and dopamine in the brain. The first recorded human use of MDEA was in 1976 by Alexander25 KB (3,654 words) - 23:46, 21 April 2024
- Stimulants facilitate the activity of the monoamine neurotransmitters, i.e., dopamine, norepinephrine and serotonin, in the central (CNS) and peripheral nervous22 KB (3,211 words) - 19:11, 7 April 2024
- 4-hydroxyphenylalanine) is a non-essential amino acid that serves a precursor to dopamine, adrenaline and norepinephrine in the human body. As a supplement, it is14 KB (2,109 words) - 23:22, 21 April 2024
- cocaine are mediated by DAT inhibition, and an increase of exocytosis of dopamine through the cell membrane. Amphetamine reverses the direction of DAT and5 KB (1,411 words) - 18:49, 5 May 2024
- dichloropane on the central nervous system is the blockade of the serotonin, dopamine, and norepinephrine transporter. This substance acts as a triple reuptake20 KB (2,747 words) - 00:19, 1 August 2022
- adjusted accordingly. 5-APB is a triple reuptake inhibitor for norepinephrine, dopamine and serotonin as well as being an agonist for the 5-HT2A and 5-HT2B receptors14 KB (2,336 words) - 23:43, 21 April 2024
- potent serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with very poor affinity for SERT. This allows dopamine, serotonin and norepinephrine18 KB (2,677 words) - 06:56, 28 April 2024
- pharmacology, although it likely acts by increasing levels of norepinephrine and dopamine in the brain. N-Ethylhexedrone was first synthesized by Boehringer Ingelheim25 KB (3,455 words) - 23:45, 21 April 2024
- induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons". The Journal of Neuroscience8 KB (888 words) - 18:33, 30 April 2024
- reuptake inhibitor, and that it releases the neurotransmitters: serotonin, dopamine, and norepinephrine. 2-FEA likely creates it effects by acting as a releasing13 KB (1,917 words) - 18:16, 30 April 2024
- designer drug pentedrone and α-PVP, which both act as a potent norepinephrine-dopamine reuptake inhibitors (NDRI), although no substantial research on the pharmacology21 KB (3,212 words) - 09:58, 30 May 2023
- reuptake inhibition of neurotransmitters such as serotonin, noradrenaline and dopamine are also thought to be involved to an extent. This can result in bufotenin16 KB (2,273 words) - 19:54, 7 April 2024
- acts as both a dopamine and norepinephrine releasing agent. This means it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters11 KB (1,914 words) - 23:46, 21 April 2024
- acts as reuptake inhibitor of glutamine and glutamate. Theanine increases dopamine, GABA, and glycine levels in various areas of the brain. It also affects15 KB (1,935 words) - 23:24, 21 April 2024
- acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters. However, relative to MDMA, it is considerably10 KB (2,183 words) - 19:02, 2 August 2022
- 5-HT2C and 5-HT6 receptors. It can also be expected to act as an agonist at dopamine receptors such as D2. The psychedelic effects are believed to come from35 KB (4,592 words) - 06:53, 10 December 2023
- direct effects on monoamines like dopamine and serotonin. Tianeptine slightly increases extracellular levels of dopamine, although it is not known how exactly20 KB (2,399 words) - 00:17, 6 May 2024
- the sense that it inhibits serotonin reuptake in addition to inhibiting dopamine reuptake. It also increases levels of norepinephrine, but its means of14 KB (1,794 words) - 23:23, 21 April 2024
- reuptake inhibitor of the monoamine neurotransmitters known as serotonin, dopamine and noradrenaline which are the global neurotransmitters that modulate26 KB (4,015 words) - 23:44, 21 April 2024
- binding activity at a wide range of monoamine receptors, such as those for dopamine and norepinephrine. However, there is currently no data to support these27 KB (3,642 words) - 18:48, 12 November 2022
- production or availability of chemicals such as acetylcholine, norepinephrine, dopamine, beta-endorphin and serotonin in the brain and other parts of the body53 KB (5,335 words) - 06:57, 15 May 2024
- (PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M21 KB (2,634 words) - 00:21, 11 December 2023
- although it likely produces its effects by increasing levels of serotonin, dopamine, and norepinephrine in the brain. Ephylone was developed in the 1960s by17 KB (2,604 words) - 22:15, 31 July 2022
- other simple substituted cathinone, it most likely acts principally as a dopamine and norepinephrine reuptake inhibitor. It however has been shown that ETH-CAT17 KB (2,584 words) - 12:23, 5 April 2024
- “hole”. Although vendors of diphenidine have stated the compound acts as a dopamine-reuptake inhibitor and a serotonin reuptake inhibitor with µ-opioid affinity20 KB (2,560 words) - 20:28, 17 January 2024
- also has effects on most of the other major neurotransmitters, including dopamine, acetylcholine, serotonin, and, in high doses, on norepinephrine, and to29 KB (3,603 words) - 00:00, 10 May 2024
- and PKC) signaling, causes dopamine transporter (DAT) phosphorylation. Both PKA and PKC result in non-competitive dopamine reuptake inhibition, although20 KB (2,813 words) - 21:23, 25 October 2023
- Kava's consituents have a sedative effect and act mainly on the GABA and dopamine receptors, as well as the sodium and calcium ion channels, but have also12 KB (1,783 words) - 07:02, 29 October 2023
- Methiopropamine functions as a selective norepinephrine-dopamine releasing agent. This allows dopamine and norepinephrine to accumulate within the brain, resulting13 KB (2,010 words) - 00:43, 1 August 2022
- compounds known as substituted cathinones. Pentedrone acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). Pentedrone was first detected being sold online17 KB (2,503 words) - 00:26, 6 May 2024
- move them into it. Anti-dopaminergics - Because promethazine also blocks dopamine receptors, other drugs and substances that do this will increase the chances12 KB (1,621 words) - 00:22, 6 May 2024
- haloperidol has a diverse pharmacological profile. Primarily, haloperidol acts on dopamine D2 receptors as an antagonist, as well as a D3 inverse agonist. Haloperidol8 KB (955 words) - 03:21, 11 May 2024
- Additionally, studies have shown that LSD possesses binding efficacy at all dopamine and all norepinephrine receptors. Most serotonergic psychedelics are not100 KB (12,100 words) - 08:20, 3 January 2024
- investigation. In contrast to LSD, this compound has no significant effect on dopamine receptors and only affects the noradrenergic system at very high dosages40 KB (4,715 words) - 16:45, 25 January 2024
- Administration of alprazolam has been demonstrated to elicit an increase in striatal dopamine concentrations. This results in effects including reduced anxiety, muscle25 KB (3,914 words) - 14:31, 16 April 2024
- mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These are the neurotransmitters in charge of pleasure, reward, motivation18 KB (2,647 words) - 23:46, 21 April 2024
- selective ligand for the NMDA receptor without appreciable affinity for the dopamine transporter. Disclaimer: The effects listed below cite the Subjective Effect13 KB (1,828 words) - 21:19, 21 July 2022
- mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These are the neurotransmitters in charge of pleasure, reward, motivation17 KB (2,532 words) - 22:27, 31 July 2022