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76 (8): 1169–1174. ISSN 0002-838X.  https://en.wikipedia.org/wiki/Monoamine_releasing_agent#Activity_profiles Kirkpatrick, M. G., Gunderson, E. W., Johanson

fluorinated analogue of amphetamine. 4-Fluoroamphetamine acts as a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine producing

drugs such as MAOIs, RIMAs, stimulants and any substance which act as a releasing agent or reuptake inhibitor of neurotransmitters such as serotonin and dopamine

Opioid ⋅ Phenethylamine ⋅ Research chemicals ⋅ Reuptake inhibitor ⋅ Releasing agent ⋅ Substituted amphetamine ⋅ Substituted cathinone ⋅ Substituted pyrrolidine

(SERT), respectively. 6-APB also possesses additional activity as a releasing agent of these monoamine neurotransmitters. 6-APB is a potent full agonist

methylated analog of the hemostatic agent hydrastinine. There are no indications of interest in MDMA as an active agent itself. It was not mentioned again

structural analog 4-FA, 4-Fluoromethamphetamine is thought to act as a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine, producing

MDMA: 3-MeO-PCP acts as a mild serotonin releasing agent and could interact negatively with the serotonin release of MDMA Austria: 3-MeO-PCP is illegal to

signalling act as reuptake inhibitors (NDRIs, e.g. methylphenidate), releasing agents (NDRAs, e.g. amphetamine) or receptor ligands (e.g yohimbine). Stimulants

Additionally, it sees widespread illicit use as a performance enhancing agent and recreational substance. Subjective effects include stimulation, focus

primarily as a serotonin-norepinephrine-dopamine reuptake inhibitor and releasing agent.[citation needed] However, MDA is significantly more potent by weight

psychedelic αMT acts as a relatively balanced reuptake inhibitor and releasing agent of the main three monoamines; serotonin, norepinephrine, and dopamine

acts as a putatively non-neurotoxic and highly selective serotonin releasing agent (SSRA) with neglible effects on dopamine and norepinephrine. MDAI was

noradrenaline reuptake. Tramadol acts as an opioid receptor agonist, serotonin releasing agent, norepinephrine reuptake inhibitor, NMDA receptor antagonist, 5-HT2C

this furan ring with 5-APDB, 5-MAPDB and 6-MAPDB. 6-APDB acts as a releasing agent and triple reuptake inhibitor of the monoamine neurotransmitters known

function. There is no evidence that releasing agents are directly neurotoxic in humans. However, large doses of releasing agents may cause indirect neurotoxicity

methylphenidate is a dopamine reuptake inhibitor while amphetamine is both a releasing agent and reuptake inhibitor of dopamine and norepinephrine. Each of these

widely used substances in the world. It is also used as an antiherbivore agent to deter plant predation and has been used as an insecticide in the past

explain the superior CNS-depressant effects of these agents to alternative GABA potentiating agents such as benzodiazepines and quinazolinones. At higher

with MDA, MDAI and MDMA. Methylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These neurotransmitters

sometimes medicinal, psychedelic effects. The co-consumption of an MAOI agent is necessary for the combination to work, as the DMT molecule (which is a

clonidine first saw clinical use in 1966. As the first anti-hypertensive agent with a clearly identifiable central site of action, clonidine has been an

Referan, and systematically as N-anisoyl-2-pyrrolidinone) is a nootropic agent belonging to the racetam family of drugs. Although it is one of the first

it most likely acts primarily as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine

with MAOIs, RIMAs, SSRIs, stimulants or any substance which acts as a releasing agent or reuptake inhibitor of monoamine neurotransmitters. Disclaimer: The

ring with other entactogens like MDMA, MDA and MDAI. MDEA acts as a releasing agent and reuptake inhibitor of the monoamine neurotransmitters serotonin

com/science/article/pii/S0378427415300333. “Ephenidine: A New Psychoactive Agent with Ketamine-like NMDA Receptor Antagonist Properties.” Neuropharmacology

content listed within this portal. Agonist Antagonist Reuptake inhibitor Releasing agent Inverse agonist Positive allosteric modulator Negative allosteric modulator

Memantine was first synthesized by Eli Lilly and Company in 1968 as a potential agent to treat diabetes.[citation needed] Memantine is classified as an NMDA receptor

dopamine, norepinephrine, and serotonin in the brain by acting as a releasing agent of said neurotransmitters and/or by binding to and partially blocking

In the past, alcohol was believed to be a non-specific pharmacological agent affecting many neurotransmitter systems in the brain. Although this notion

ring. Given its chemical structure, mephedrone is likely to act as a releasing agent and a reuptake inhibitor for monoamine neurotransmitters such as dopamine

that it releases the neurotransmitters: serotonin, dopamine, and norepinephrine. 2-FEA likely creates it effects by acting as a releasing agent of said

substitutions at similar positions, it most likely acts primarily as a triple releasing agent of serotonin, dopamine, and norepinephrine.[citation needed] Disclaimer:

consumed. Its mechanism of action appears to function by acting as a releasing agent for dopamine and norepinephrine, increasing their concentrations in

it most likely acts primarily as both a dopamine and norepinephrine releasing agent, with modest selectivity for serotonin. This means it effectively increases

which have fatigue as a symptom. Modafinil has also been used as a doping agent by various athletes due to its ability to produce physical stimulation. It

speculated that 5-MAPB acts as a releasing agent for the previously mentioned neurotransmitters. As a result, releasing agents such as 5-MAPB may exert their

so-called "rebound" effect reported by individuals using GHB as a sleeping agent wherein they awake suddenly after several hours of GHB-induced deep sleep

Acuña-Castroviejo, D., Camello, P. J. (2010). "Melatonin, a potential therapeutic agent for smooth muscle-related pathological conditions and aging". Current Medicinal

may also be due to its activity as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, although new research has shown very low

Phenotropil and Carphedon) is a central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. Although it is one of the first

the preparation of prolintane for use as a mild CNS stimulant, wakefulness agent, and cessation aid for cocaine addiction. It has been marketed in Europe

Oxiracetam (ISF 2522) is a mild central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. Although it is one of the first

literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of

as a dietary supplement. N-Acetylcysteine (NAC) is emerging as a useful agent in the treatment of psychiatric disorders. It is currently being explored

5-Methoxylicarin A) have been shown to act as endo-cannabinoid modulating agents by inhibiting the enzymes FAAH and MAGL. In comparison to datura or diphenhydramine

component is however much less common and intense than it is with serotonin releasing agents such as MDMA. Watery eyes Muscle contractions Olfactory hallucination

Methamphetamine. PMMA, like PMA most likely acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters

Federation of Neurological Societies recommends pregabalin as a first line agent for the treatment of pain associated with diabetic neuropathy, post-herpetic

amphetamines, it is thought that it acts as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine

2-FMA. 2-AI most likely acts as both a dopamine and norepinephrine releasing agent. This means it effectively boosts the levels of the norepinephrine and

to act not only as a serotonin reuptake inhibitor but as a serotonin releasing agent as well. mCPP's strongest actions are at the 5-HT2B and 5-HT2C receptors

L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent". Journal of Herbal Pharmacotherapy. 6 (2): 21–30. ISSN 1522-8940.  Kakuda

processing faults during synthesis, the addition of harmful or benign cutting agents, or the substitution of significantly more potent and dangerous analogous

with MDA, MDAI and MDMA. Butylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These are the neurotransmitters

high-speed rollercoaster ride." When ingested in combination with a MAOI or RIMA agent, it becomes active orally and significantly longer lasting, immersive, and

4-Methoxy analog of amphetamine. PMA acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters

similar mid-level centrally acting agents in combination with non-opioid analgesics, antihistamines, vitamins, inert GI agents like kaolin & pectin, mild laxatives

"Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin". Synapse. 39 (1): 32–41

with MDA, MDAI and MDMA. Ethylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These are the neurotransmitters

schres.2013.12.018. ISSN 0920-9964.  3-HO-PCP (Tripsit) | https://wiki.tripsit.me/wiki/3-HO-PCP https://www.zakonyprolidi.cz/cs/2013-463?text=o+sezname

the 5-HT2A and 5-HT2B receptors. It has also been speculated that 5-APB acts as a releasing agent for the previously mentioned neurotransmitters. This means it effectively

http://www.drugs.com/international/fentanyl.html Fentanyl: Incapacitating Agent, NIOSH, CDC, 2021  Mutschler, E., ed. (2001). Arzneimittelwirkungen: Lehrbuch

with MAOIs, RIMAs, SSRIs, stimulants or any substance which acts as a releasing agent or reuptake inhibitor of monoamine neurotransmitters. 5-MeO-DMT is O-demethylated

research suggests that heating it at 340°C (644°F) unbinds the acetyl group, releasing toxic ketene gas. Chemical conversion: acetic anhydride + Δ-9-THC/Δ-8-THC

research suggests that heating it at 340°C (644°F) unbinds the acetyl group, releasing toxic ketene gas. Chemical conversion: acetic anhydride + Δ-9-THC/Δ-8-THC

adrenergic receptors. It also acts as a NDRA (norepinephrine-dopamine releasing agent). Ephedrine, a sympathomimetic amine, acts on part of the sympathetic

tank or whippet. Releasing the gas into a balloon first allows the gas to warm before being administered. Medical nitrous oxide is released slowly. Hypoxia

is strongly discouraged. Entactogens - Combining SSRIs with serotonin releasers such as MDMA, mephedrone, and AMT can result in serotonin syndrome. Tramadol

acuminata - DMT-Nexus Wiki  Acacia baileyana Wikipedia | https://en.wikipedia.org/wiki/Acacia_baileyana Acacia baileyana - DMT-Nexus Wiki  Acacia burkittii

that NM-2-AI most likely acts as both a dopamine and norepinephrine releasing agent. This means it effectively boosts the levels of the norepinephrine and

Many users claim kratom is useful in treating opioid addiction as a weaning agent, particularly during the initial withdrawal phase.[citation needed] Kratom

additional methoxy group bonded to the α-methyl group. Mexedrone acts as a releasing agent of serotonin and a reuptake inhibitor for monoamine neurotransmitters

much less prevalent and intense than those that occur with serotonin releasing agents such as MDMA. Seizure[citation needed] - This is a rarely observed

component is however much less common and intense than it is with serotonin releasing agents such as MDMA. Seizure[citation needed] - This is a rare effect but

constituent. Methiopropamine functions as a selective norepinephrine-dopamine releasing agent. This allows dopamine and norepinephrine to accumulate within the brain

tolerance. Users taking hallucinogenic doses should have a hypertensive agent available or a supervisor present. Exercise extreme caution when attempting

much less prevalent and intense than those that occur with serotonin releasing agents such as MDMA. Seizure[citation needed] - Psychedelics are known to

Propylhexedrine affects the central nervous system (CNS) by acting as a releasing agent for the monoamine neurotransmitters dopamine, norepinephrine, and serotonin

monkeys, without the adverse effects associated with older dopamine releasing agent (e.g., amphetamine).[citation needed] Despite this, ethcathinone may

substituted cathinones, which display both reuptake-inhibition and releasing agent properties, pentedrone has been shown to act as a pure reuptake inhibitor

Sames, D. (15 July 2014). "The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist". Translational Psychiatry. 4:

pharmaceutical company Boehringer Ingelheim in 1964 as a potential anorexigenic agent. The patent describes its synthesis together with other derivatives of aminoketone

drugs such as MAOIs, RIMAs, stimulants and any substance which act as a releasing agent or reuptake inhibitor of neurotransmitters such as serotonin and dopamine

decrease sleepiness are not fully understood, evidence suggests that these agents promote wakefulness by acting directly or indirectly on many components

reducing pain, causing sleepiness, and feelings of pleasure. They can be released in response to pain, strenuous exercise, orgasm, or general excitement

methamphetamine, desomorphine made this way is often contaminated with various agents. The street name in Russia for homemade desomorphine is krokodil (Russian:

reputation or escrow system. Trusted members of the community may act as escrow agents. Centralized Markets. The original "Silkroad" was the first of this kind

spray guide Staggering guide Edit Agonist Antagonist Reuptake inhibitor Releasing agent Inverse agonist Positive allosteric modulator Negative allosteric modulator