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  • heavy. Responsible use Shulgin rating system Duration Routes of administration The Importance of Measured Doses (Erowid) Erowid Psychoactive Vaults : Dose 
    5 KB (1,438 words) - 23:18, 21 April 2024
  • which will calculate the amount of drug and solvent needed as well as the concentration. Main article: Routes of administration Oral cavity: Avoiding sublingual
    37 KB (3,944 words) - 23:17, 21 April 2024
  • conceptual thinking, euphoria, and depersonalization / dissociation. Routes of administration include oral, smoking, insufflation or injection. The effects are
    25 KB (3,130 words) - 14:33, 16 April 2024
  • that of 3-MeO-PCP but with a potentially higher risk of inducing states of mania, delusions and potential psychosis due to the greater degree of euphoric
    20 KB (2,787 words) - 17:34, 17 March 2024
  • variable in effect. (Description of distinguishing properties compared to other substances?) Its most common routes of administration include oral, sublingual
    10 KB (1,405 words) - 18:40, 20 August 2020
  • as a shorter duration. However, this route of administration is highly advised against due to the difficulties of measuring and handling substances that
    19 KB (3,278 words) - 19:48, 19 July 2022
  • dose-response curves. Responsible use Set and setting Dosage classification Routes of administration Trip sitter Dosage form (Wikipedia) American Weigh Scales, Inc
    9 KB (1,092 words) - 23:18, 21 April 2024
  • to the administration of DMT crystals): Rectal administration of DMT crystals (from 15 to 70 mg; from 4.5 to 7 hours) Sublingual administration of DMT crystal
    58 KB (7,681 words) - 22:15, 14 May 2024
  • based on the route of administration used. For example, it is especially present when smoked or vaporized, due to the relative abruptness of the substance
    20 KB (2,510 words) - 17:29, 17 March 2024
  • prescribed in the treatment of [https://en.wikipedia.org/wiki/Bipolar_disorder bipolar disorder. There is a large body of anecdotal evidence that suggests
    26 KB (4,063 words) - 23:35, 21 April 2024
  • the chances of syncope due to turbulent blood flow during valve operation. The rewarding mechanisms of cocaine are reversed by administration of amphetamine
    21 KB (3,439 words) - 15:42, 30 July 2022
  • as the use of soma in the origins of Hinduism, and many of these uses continue into the modern day. Some common examples of this are the use of wine containing
    70 KB (630 words) - 04:11, 16 May 2024
  • grinding of the teeth comparable to that of MDMA and traditional stimulants such as amphetamine. Perception of bodily lightness - In terms of the body’s
    28 KB (4,417 words) - 14:00, 16 April 2024
  • based on the route of administration used. For example, it is especially present when smoked or vaporized, due to the relative abruptness of the substance
    16 KB (2,138 words) - 20:47, 21 July 2022
  • be solely used for the purposes of scientific research. The use of research chemicals carries more risks than the use of more common, well-studied substances
    19 KB (2,209 words) - 23:08, 21 April 2024
  • Psychoactive class: Opioid/Stimulant Chemical class: Morphian Routes of Administration WARNING: Always start with lower doses due to differences between
    6 KB (900 words) - 21:25, 29 March 2021
  • (PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M
    18 KB (2,543 words) - 21:36, 21 July 2022
  • prescribed in the treatment of [https://en.wikipedia.org/wiki/Bipolar_disorder bipolar disorder. There is a large body of anecdotal evidence that suggests
    19 KB (3,287 words) - 22:22, 19 July 2022
  • the chances of syncope due to turbulent blood flow during valve operation. The rewarding mechanisms of cocaine are reversed by administration of amphetamine
    41 KB (5,798 words) - 13:29, 16 April 2024
  • the chances of syncope due to turbulent blood flow during valve operation. The rewarding mechanisms of cocaine are reversed by administration of amphetamine
    41 KB (5,610 words) - 19:01, 7 April 2024
  • than the rest of the 25x-NBOMe series with a total duration of 6 hours and a peak duration of 2 hours. It is moderately active at a dose of one milligram
    18 KB (3,141 words) - 20:58, 19 July 2022
  • Tutorial index List of reagent testing color charts (Wikipedia) Color Test Reagents/Kits for Preliminary Identification of Drugs of Abuse (Erowid) Ecstasy
    23 KB (1,192 words) - 17:50, 19 March 2024
  • Experience index (category PsychonautWiki) (section Combinations of psychedelics)
    the substance taken, dose and route of administration, the set and setting, the range of effects experienced, or the plots of any specific hallucinations
    2 KB (4,008 words) - 23:00, 21 April 2024
  • sublingually due to the high bioavailability of these routes. As with benzodiazepines, the sudden discontinuation of thienodiazepines can be dangerous or even
    30 KB (3,506 words) - 14:22, 16 April 2024
  • other classes of hallucinogen, this effect occurs more frequently than that of any other at moderate to heavy doses and is the defining feature of the experience
    26 KB (2,932 words) - 14:16, 16 April 2024
  • based on the route of administration used. For example, it is especially present when smoked or vaporized, due to the relative abruptness of the substance
    25 KB (3,520 words) - 21:44, 6 May 2024
  • molecule of the benzofuran class. The benzofuran class of substances are members of the amphetamine and phenylethylamine classes. Molecules of this class
    33 KB (4,870 words) - 14:34, 16 April 2024
  • the chances of syncope due to turbulent blood flow during valve operation. The rewarding mechanisms of cocaine are reversed by administration of amphetamine
    21 KB (3,467 words) - 16:14, 30 July 2022
  • carbon R4 of the phenyl ring. 2C-B belongs to the 2C family of phenethylamines, all of which possess methoxy groups on the 2 and 5 positions of the benzene
    36 KB (4,745 words) - 16:35, 7 April 2024
  • responsible context, the administration of repeated or high dosages of MDMA is most certainly neurotoxic in some form. Administration of MDMA causes subsequent
    85 KB (10,499 words) - 14:24, 16 April 2024
  • changes in the living human brain". Proceedings of the National Academy of Sciences of the United States of America. 92 (7): 2775–2779. ISSN 0027-8424.  http://www
    22 KB (2,595 words) - 13:26, 16 April 2024
  • incidents of psychological and physical harm have been attributed to the use of MDPV, including an unusually large number of fatalities. A total of 107 non-fatal
    23 KB (3,267 words) - 23:45, 21 April 2024
  • each day for a prolonged period of time instead of stopping abruptly. Flunitrazepam was discovered at Roche as part of the benzodiazepine work led by Leo
    22 KB (2,689 words) - 20:55, 7 April 2024
  • xanthine. Theobromine has an elimination half-life of 7.1±0.7 hours The principal mechanism of action of theobromine is as a nonselective antagonist at the
    14 KB (1,908 words) - 08:31, 1 November 2023
  • motivation enhancement, ego inflation, increased libido, and euphoria. Routes of administration include insufflation ("snorting" or "sniffing") and occasionally
    47 KB (6,322 words) - 08:08, 3 May 2024
  • conceptual thinking, euphoria, and depersonalization / dissociation. Routes of administration include oral, smoking, insufflation or injection. Rolicyclidine
    21 KB (2,634 words) - 00:21, 11 December 2023
  • often results in the loss of much of the final product. Dosage and preparation can be found in other parts of the psychonaut wiki. This is for informational
    9 KB (1,571 words) - 01:36, 8 December 2022
  • measuring the dose with the naked eye instead of a reliable milligram scale) and non-oral routes of administration. Volumetric liquid dosing is commonly recommended
    22 KB (3,193 words) - 17:38, 18 January 2024
  • stimulant-entactogen substance of the cathinone class. It is a structural analog of mephedrone (4-MMC). The mechanism of action is not fully studied, but
    18 KB (2,590 words) - 21:20, 30 April 2024
  • level trips. Perception of eternalism Perception of self-design Perception of predeterminism Perceived exposure to inner mechanics of consciousness Unity and
    26 KB (3,619 words) - 19:56, 7 April 2024
  • powdered form can be taken orally as well as via injection. Any other routes of administration other than oral are not recommended because diphenhydramine burns
    33 KB (4,164 words) - 20:42, 12 May 2024
  • analog of an ether analog of DOB, which would make it controlled under Buchstabe C. It could be considered an ether analog of an ether analog of para-bromoamphetamine
    20 KB (2,786 words) - 23:37, 21 April 2024
  • based on the route of administration used. For example, it is especially present when smoked or vaporized, due to the relative abruptness of the substance
    15 KB (1,980 words) - 20:44, 21 July 2022
  • approved by the Food and Drug Administration for the treatment of epilepsy disorders. The U.S. Drug Enforcement Administration has assigned Epidiolex a Schedule
    23 KB (2,978 words) - 07:22, 8 April 2023
  • 2C-T-2 (category PsychonautWiki articles needing factual verification from October 2020)
    psychedelic substance of the phenethylamine chemical class that produces psychedelic effects when administered. It is a member of the 2C-x family of psychedelic
    22 KB (2,627 words) - 23:08, 29 May 2021
  • the patients' perception of the world. A full reduction or disappearance of depersonalization occurred within the interval of 1–4 hours and, in some patients
    16 KB (2,164 words) - 23:20, 19 December 2022
  • Safer injection guide Sharing injection materials Responsible use Routes of administration North America Syringe Exchange Network Javed, Z; Burk, K; Facente
    1 KB (230 words) - 19:22, 3 September 2022
  • associated with the use of a synthetic cannabinoid product". Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology.
    27 KB (3,598 words) - 22:59, 21 April 2024
  • be capable of causing psychological dependence among users. Tolerance to many of the effects of omberacetam develops over several weeks of prolonged and
    11 KB (1,343 words) - 23:24, 21 April 2024
  • the chances of syncope due to turbulent blood flow during valve operation. The rewarding mechanisms of cocaine are reversed by administration of amphetamine
    23 KB (3,617 words) - 09:16, 17 April 2024
  • behavioral actions of this compound strongly suggest that the 5-HT2A receptor is an important site of action for DPT, but the modulatory actions of a 5-HT1A receptor
    22 KB (2,679 words) - 15:39, 28 January 2023
  • subjects after the administration of a single dose of methylphenidate and ethanol". Drug Metabolism and Disposition: The Biological Fate of Chemicals. 28 (6):
    31 KB (4,254 words) - 15:15, 6 May 2024
  • "Lack of effects of GHB precursors GBL and 1,4-BD following i.c.v. administration in rats: GBL and 1,4-BD after i.p. and i.c.v. administration". European
    19 KB (2,729 words) - 17:49, 20 March 2024
  • is a novel dissociative substance of the arylcyclohexylamine class. It is a structural analog of MXE. The mechanism of action is not known, but it is likely
    17 KB (2,265 words) - 18:27, 14 January 2024
  • (1996). "[Severe hyperthermia caused by sudden withdrawal of continuous intrathecal administration of baclofen]". Annales Francaises D’anesthesie Et De Reanimation
    16 KB (1,962 words) - 02:04, 19 March 2024
  • a quick onset of effects and rapid offset. There is little information available about the use of APICA via other routes of administration, although as
    17 KB (2,044 words) - 23:41, 21 April 2024
  • to the sedative-hypnotic effects develops within a couple of days of repeated administration. After that, it takes about 3 - 7 days for the tolerance to
    12 KB (1,829 words) - 23:50, 21 April 2024
  • symptoms of the lower urinary tract. A study conducted in 2015 demonstrated that co-administration of EGCG (10mM/kg) in rats receiving a daily dose of ketamine
    57 KB (7,569 words) - 21:34, 6 May 2024
  • trials involving the administration of 1000mg to 1600mg of modafinil per day for 7 to 21 consecutive days. Intentional acute overdoses of 4500mg and 4000mg
    19 KB (3,104 words) - 11:29, 16 April 2024
  • reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism. It is also worth noting
    11 KB (1,643 words) - 00:24, 10 May 2024
  • anecdotal reports of users experiencing painful chemical burns caused by ingesting pramiracetam powder sublingually. Other routes of administration do not seem
    8 KB (1,030 words) - 20:10, 2 August 2022
  • There is some evidence that suggests that co-administration of LSD with MDMA increases the neurotoxicity of the latter, and this may extend to 1cP-MiPLA
    23 KB (2,866 words) - 20:03, 16 December 2022
  • the blood level concentrations of the drug increases. Intravenous injection is the fastest route of drug administration, causing blood concentrations to
    27 KB (4,225 words) - 13:14, 16 April 2024
  • as if they are constantly on the verge of passing out instead of engaging in physical activities. This sense of sleep deprivation increases proportional
    4 KB (510 words) - 11:41, 22 June 2023
  • particular effect is uncommon during the first half of the trip but capable of manifesting itself towards the end of the experience, particularly if sleep deprivation
    25 KB (2,825 words) - 16:14, 28 November 2022
  • Loved"). It is a member of the 2C-x family of psychedelic phenethylamines, all of which were derived from the systematic modification of the mescaline molecule
    22 KB (2,709 words) - 23:09, 29 May 2021
  • subjects after the administration of a single dose of methylphenidate and ethanol". Drug Metabolism and Disposition: The Biological Fate of Chemicals. 28 (6):
    18 KB (2,561 words) - 14:02, 16 April 2024
  • intravenous administration of bufotenin results in excretion of (70%) of injected drug in the form of 5-HIAA, an endogenous metabolite of serotonin, while
    16 KB (2,273 words) - 19:54, 7 April 2024
  • contraction of groups of muscles), but is used off-label for other conditions. In the United States, it is not approved by the Food and Drug Administration for
    12 KB (1,475 words) - 00:39, 15 April 2023
  • reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism. It is also worth noting
    11 KB (1,524 words) - 16:45, 29 May 2021
  • structure of LSA contains a core structure of lysergic acid with an amine functional group bound to RN. The structure of lysergic acid is composed of a bicyclic
    29 KB (3,883 words) - 13:23, 16 April 2024
  • reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism. It is also worth noting
    10 KB (1,423 words) - 17:12, 29 May 2021
  • events induced by GHB administration. These findings may explain the paradoxical mix of sedative and stimulatory properties of GHB as well as the so-called
    35 KB (4,460 words) - 13:32, 16 April 2024
  • than that of clozapine. Other: The use of low doses of quetiapine for insomnia, while common, is not recommended; there is little evidence of benefit and
    26 KB (3,070 words) - 00:36, 28 April 2024
  • a psychedelic substance of the phenethylamine class. It is a member of the 2C-x family of psychedelic phenethylamines, all of which were derived from the
    19 KB (2,571 words) - 21:32, 14 November 2023
  • reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism. It is also worth noting
    9 KB (1,364 words) - 16:46, 29 May 2021
  • psychedelic substance of the phenethylamine chemical class that produces psychedelic effects when administered. It is a member of the 2C-x family of psychedelic
    18 KB (2,002 words) - 06:06, 12 August 2022
  • this substance to ensure the administration of the intended dose. As with other NMDA receptor antagonists, the chronic use of 3-MeO-PCMo can be considered
    15 KB (2,255 words) - 21:04, 21 July 2022
  • 2-Aminoindane, is a structural analogue of amphetamine. It features the R3 terminal carbon of the propane chain of amphetamine bound to the benzene ring
    12 KB (1,928 words) - 23:42, 21 April 2024
  • in the context of social settings in which one is within the company of others, and only at lower, non-impairing doses. These feelings of sociability, affection
    15 KB (2,058 words) - 05:50, 30 June 2022
  • periods of time. It is highly recommended to taper one's dose by gradually lowering the amount taken each day for a prolonged period of time instead of stopping
    20 KB (2,574 words) - 20:48, 7 April 2024
  • lesser-known psychedelic substance of the phenethylamine class. It is a member of the 2C-x family of psychedelic phenethylamines, all of which are close relatives
    13 KB (1,528 words) - 23:08, 29 May 2021
  • binding than Buprenorphine, as well as being inactive through most routes of administration. Warning: Many psychoactive substances that are reasonably safe
    15 KB (2,602 words) - 23:49, 21 April 2024
  • substances ⋅ List of entheogens ⋅ List of pharmaceuticals ⋅ List of polysubstance combinations ⋅ List of precursors ⋅ List of prodrugs ⋅ List of psychoactive
    21 KB (1,004 words) - 23:38, 13 May 2024
  • them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually an almost identical equivalent of the famous “k-hole.” Disclaimer:
    12 KB (1,610 words) - 22:13, 5 December 2023
  • Kingdom: 2-FEA is considered a Class A drug as a result of the amphetamine analogue clause of the Misuse of Drugs Act 1971. Responsible use Research chemical
    13 KB (1,917 words) - 18:16, 30 April 2024
  • grinding of the teeth comparable to that of MDMA and traditional stimulants such as amphetamine. Perception of bodily lightness - In terms of the body’s
    19 KB (2,640 words) - 07:18, 30 June 2022
  • smaller volume of water. The hydrochloride salt is soluble in three parts of water, whereas a gram of morphine hydrochloride dissolves in 16 ml of water; for
    15 KB (2,521 words) - 19:28, 7 April 2024
  • to shift the position of one's body and prolonged tensing of unusual combinations of muscle groups. Physical euphoria - Feelings of frequent but unpredictable
    22 KB (2,969 words) - 13:42, 16 April 2024
  • terminal amine RN of its tryptamine backbone (MET). 4-AcO-MET is an acetate ester analog of 4-HO-MET and the N-substituted ethyl homolog of 4-AcO-DMT. Further
    14 KB (2,059 words) - 17:03, 17 March 2024
  • reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism. It is also worth noting
    13 KB (1,611 words) - 15:10, 10 March 2023
  • by suppositories of ergotamine tartrate and caffeine (for the relief of migraine) and of chlorobutanol and caffeine (for the treatment of hyperemesis). However
    29 KB (3,603 words) - 00:00, 10 May 2024
  • (February 2016). "Pharmacokinetics of Memantine after a Single and Multiple Dose of Oral and Patch Administration in Rats". Basic & Clinical Pharmacology
    17 KB (2,270 words) - 05:20, 1 May 2024
  • disconnection of neurons leads to the general loss of bodily sensation, motor coordination, memory recall and eventually this substance's equivalent of the “k-hole
    16 KB (2,011 words) - 23:32, 21 April 2024
  • terminal amine RN of its tryptamine backbone. EPT is the N-ethyl analog of DPT and the N-propyl analog of DET. It is also an analog of 4-HO-EPT and 4-AcO-EPT
    9 KB (1,156 words) - 05:07, 30 June 2022
  • Francisco López-Munoz, the "discovery of haloperidol at the end of the 1950s constitutes one of the greatest advances of 20th century psychiatry." This antipsychotic
    8 KB (955 words) - 03:21, 11 May 2024
  • laboratory of David E. Nichols who prepared a series of mescaline analogues, including proscaline, jimscaline, isoproscaline, and others. The effects of escaline
    12 KB (1,512 words) - 00:01, 21 December 2023
  • reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism. It is also worth noting
    14 KB (1,519 words) - 23:39, 14 January 2022
  • Flurazepam belongs to the benzodiazepine class of drugs, characterized by their ability to enhance the effect of the neurotransmitter gamma-aminobutyric acid
    2 KB (240 words) - 21:42, 5 May 2024
  • psychedelic substance of the phenethylamine class that produces psychedelic effects when administered. It is a member of the 2C-x family of psychedelic phenethylamines
    22 KB (3,030 words) - 21:29, 14 November 2023

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