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- 76 (8): 1169–1174. ISSN 0002-838X. https://en.wikipedia.org/wiki/Monoamine_releasing_agent#Activity_profiles Kirkpatrick, M. G., Gunderson, E. W., Johanson41 KB (5,798 words) - 13:29, 16 April 2024
- fluorinated analogue of amphetamine. 4-Fluoroamphetamine acts as a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine producing21 KB (3,439 words) - 15:42, 30 July 2022
- drugs such as MAOIs, RIMAs, stimulants and any substance which act as a releasing agent or reuptake inhibitor of neurotransmitters such as serotonin and dopamine19 KB (2,209 words) - 23:08, 21 April 2024
- Main Page (section Please don't crawl the wiki. Use our API instead.PsychonautWiki ❤️ Developers. Please report any obstacles.)Opioid ⋅ Phenethylamine ⋅ Research chemicals ⋅ Reuptake inhibitor ⋅ Releasing agent ⋅ Substituted amphetamine ⋅ Substituted cathinone ⋅ Substituted pyrrolidine21 KB (1,004 words) - 23:38, 13 May 2024
- (SERT), respectively. 6-APB also possesses additional activity as a releasing agent of these monoamine neurotransmitters. 6-APB is a potent full agonist33 KB (4,870 words) - 14:34, 16 April 2024
- methylated analog of the hemostatic agent hydrastinine. There are no indications of interest in MDMA as an active agent itself. It was not mentioned again85 KB (10,499 words) - 14:24, 16 April 2024
- structural analog 4-FA, 4-Fluoromethamphetamine is thought to act as a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine, producing21 KB (3,467 words) - 16:14, 30 July 2022
- MDMA: 3-MeO-PCP acts as a mild serotonin releasing agent and could interact negatively with the serotonin release of MDMA Austria: 3-MeO-PCP is illegal to25 KB (3,520 words) - 21:44, 6 May 2024
- signalling act as reuptake inhibitors (NDRIs, e.g. methylphenidate), releasing agents (NDRAs, e.g. amphetamine) or receptor ligands (e.g yohimbine). Stimulants11 KB (1,055 words) - 02:52, 12 May 2024
- Additionally, it sees widespread illicit use as a performance enhancing agent and recreational substance. Subjective effects include stimulation, focus41 KB (5,610 words) - 19:01, 7 April 2024
- primarily as a serotonin-norepinephrine-dopamine reuptake inhibitor and releasing agent.[citation needed] However, MDA is significantly more potent by weight31 KB (4,379 words) - 12:23, 6 May 2024
- psychedelic αMT acts as a relatively balanced reuptake inhibitor and releasing agent of the main three monoamines; serotonin, norepinephrine, and dopamine25 KB (2,825 words) - 16:14, 28 November 2022
- acts as a putatively non-neurotoxic and highly selective serotonin releasing agent (SSRA) with neglible effects on dopamine and norepinephrine. MDAI was17 KB (2,560 words) - 07:40, 12 October 2023
- noradrenaline reuptake. Tramadol acts as an opioid receptor agonist, serotonin releasing agent, norepinephrine reuptake inhibitor, NMDA receptor antagonist, 5-HT2C22 KB (3,211 words) - 19:11, 7 April 2024
- this furan ring with 5-APDB, 5-MAPDB and 6-MAPDB. 6-APDB acts as a releasing agent and triple reuptake inhibitor of the monoamine neurotransmitters known26 KB (4,015 words) - 23:44, 21 April 2024
- function. There is no evidence that releasing agents are directly neurotoxic in humans. However, large doses of releasing agents may cause indirect neurotoxicity19 KB (2,675 words) - 16:54, 31 March 2024
- methylphenidate is a dopamine reuptake inhibitor while amphetamine is both a releasing agent and reuptake inhibitor of dopamine and norepinephrine. Each of these31 KB (4,254 words) - 15:15, 6 May 2024
- widely used substances in the world. It is also used as an antiherbivore agent to deter plant predation and has been used as an insecticide in the past53 KB (5,335 words) - 06:57, 15 May 2024
- explain the superior CNS-depressant effects of these agents to alternative GABA potentiating agents such as benzodiazepines and quinazolinones. At higher16 KB (1,815 words) - 09:25, 14 January 2023
- with MDA, MDAI and MDMA. Methylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These neurotransmitters19 KB (2,841 words) - 14:21, 16 April 2024
- sometimes medicinal, psychedelic effects. The co-consumption of an MAOI agent is necessary for the combination to work, as the DMT molecule (which is a33 KB (3,884 words) - 07:33, 16 November 2023
- clonidine first saw clinical use in 1966. As the first anti-hypertensive agent with a clearly identifiable central site of action, clonidine has been an22 KB (2,932 words) - 13:49, 16 April 2024
- Referan, and systematically as N-anisoyl-2-pyrrolidinone) is a nootropic agent belonging to the racetam family of drugs. Although it is one of the first11 KB (1,427 words) - 22:01, 24 January 2024
- it most likely acts primarily as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine17 KB (3,024 words) - 17:25, 18 January 2024
- with MAOIs, RIMAs, SSRIs, stimulants or any substance which acts as a releasing agent or reuptake inhibitor of monoamine neurotransmitters. Disclaimer: The16 KB (2,273 words) - 19:54, 7 April 2024
- ring with other entactogens like MDMA, MDA and MDAI. MDEA acts as a releasing agent and reuptake inhibitor of the monoamine neurotransmitters serotonin25 KB (3,654 words) - 23:46, 21 April 2024
- com/science/article/pii/S0378427415300333. “Ephenidine: A New Psychoactive Agent with Ketamine-like NMDA Receptor Antagonist Properties.” Neuropharmacology25 KB (3,096 words) - 09:43, 10 May 2024
- content listed within this portal. Agonist Antagonist Reuptake inhibitor Releasing agent Inverse agonist Positive allosteric modulator Negative allosteric modulator599 bytes (162 words) - 23:00, 21 April 2024
- Memantine was first synthesized by Eli Lilly and Company in 1968 as a potential agent to treat diabetes.[citation needed] Memantine is classified as an NMDA receptor17 KB (2,270 words) - 05:20, 1 May 2024
- dopamine, norepinephrine, and serotonin in the brain by acting as a releasing agent of said neurotransmitters and/or by binding to and partially blocking19 KB (3,317 words) - 15:23, 30 July 2022
- In the past, alcohol was believed to be a non-specific pharmacological agent affecting many neurotransmitter systems in the brain. Although this notion95 KB (11,688 words) - 02:47, 12 May 2024
- ring. Given its chemical structure, mephedrone is likely to act as a releasing agent and a reuptake inhibitor for monoamine neurotransmitters such as dopamine29 KB (3,963 words) - 14:23, 16 April 2024
- that it releases the neurotransmitters: serotonin, dopamine, and norepinephrine. 2-FEA likely creates it effects by acting as a releasing agent of said13 KB (1,917 words) - 18:16, 30 April 2024
- substitutions at similar positions, it most likely acts primarily as a triple releasing agent of serotonin, dopamine, and norepinephrine.[citation needed] Disclaimer:14 KB (2,687 words) - 15:28, 30 July 2022
- consumed. Its mechanism of action appears to function by acting as a releasing agent for dopamine and norepinephrine, increasing their concentrations in15 KB (2,265 words) - 06:42, 8 September 2023
- it most likely acts primarily as both a dopamine and norepinephrine releasing agent, with modest selectivity for serotonin. This means it effectively increases15 KB (2,726 words) - 11:39, 17 February 2024
- which have fatigue as a symptom. Modafinil has also been used as a doping agent by various athletes due to its ability to produce physical stimulation. It19 KB (3,104 words) - 11:29, 16 April 2024
- speculated that 5-MAPB acts as a releasing agent for the previously mentioned neurotransmitters. As a result, releasing agents such as 5-MAPB may exert their13 KB (2,233 words) - 00:32, 31 December 2022
- so-called "rebound" effect reported by individuals using GHB as a sleeping agent wherein they awake suddenly after several hours of GHB-induced deep sleep35 KB (4,460 words) - 13:32, 16 April 2024
- Acuña-Castroviejo, D., Camello, P. J. (2010). "Melatonin, a potential therapeutic agent for smooth muscle-related pathological conditions and aging". Current Medicinal15 KB (1,896 words) - 23:12, 21 April 2024
- may also be due to its activity as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, although new research has shown very low18 KB (2,677 words) - 06:56, 28 April 2024
- Phenotropil and Carphedon) is a central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. Although it is one of the first11 KB (1,273 words) - 00:25, 6 May 2024
- the preparation of prolintane for use as a mild CNS stimulant, wakefulness agent, and cessation aid for cocaine addiction. It has been marketed in Europe11 KB (1,751 words) - 20:42, 12 September 2022
- Oxiracetam (ISF 2522) is a mild central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. Although it is one of the first9 KB (1,148 words) - 19:58, 2 August 2022
- 2C-T-2 (category PsychonautWiki articles needing factual verification from October 2020)literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of22 KB (2,627 words) - 23:08, 29 May 2021
- as a dietary supplement. N-Acetylcysteine (NAC) is emerging as a useful agent in the treatment of psychiatric disorders. It is currently being explored17 KB (1,957 words) - 17:42, 7 April 2024
- 5-Methoxylicarin A) have been shown to act as endo-cannabinoid modulating agents by inhibiting the enzymes FAAH and MAGL. In comparison to datura or diphenhydramine19 KB (2,523 words) - 07:09, 16 November 2023
- component is however much less common and intense than it is with serotonin releasing agents such as MDMA. Watery eyes Muscle contractions Olfactory hallucination40 KB (4,715 words) - 16:45, 25 January 2024
- Methamphetamine. PMMA, like PMA most likely acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters10 KB (1,254 words) - 09:30, 28 December 2022
- Federation of Neurological Societies recommends pregabalin as a first line agent for the treatment of pain associated with diabetic neuropathy, post-herpetic41 KB (5,211 words) - 12:50, 15 March 2024
- amphetamines, it is thought that it acts as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine17 KB (2,934 words) - 17:24, 18 January 2024
- 2-FMA. 2-AI most likely acts as both a dopamine and norepinephrine releasing agent. This means it effectively boosts the levels of the norepinephrine and12 KB (1,928 words) - 23:42, 21 April 2024
- to act not only as a serotonin reuptake inhibitor but as a serotonin releasing agent as well. mCPP's strongest actions are at the 5-HT2B and 5-HT2C receptors18 KB (2,483 words) - 19:42, 10 October 2023
- L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent". Journal of Herbal Pharmacotherapy. 6 (2): 21–30. ISSN 1522-8940. Kakuda15 KB (1,935 words) - 23:24, 21 April 2024
- processing faults during synthesis, the addition of harmful or benign cutting agents, or the substitution of significantly more potent and dangerous analogous27 KB (4,225 words) - 13:14, 16 April 2024
- with MDA, MDAI and MDMA. Butylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These are the neurotransmitters18 KB (2,647 words) - 23:46, 21 April 2024
- high-speed rollercoaster ride." When ingested in combination with a MAOI or RIMA agent, it becomes active orally and significantly longer lasting, immersive, and58 KB (7,681 words) - 22:15, 14 May 2024
- 4-Methoxy analog of amphetamine. PMA acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters10 KB (2,183 words) - 19:02, 2 August 2022
- similar mid-level centrally acting agents in combination with non-opioid analgesics, antihistamines, vitamins, inert GI agents like kaolin & pectin, mild laxatives27 KB (4,327 words) - 13:58, 16 April 2024
- "Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin". Synapse. 39 (1): 32–4147 KB (6,322 words) - 08:08, 3 May 2024
- with MDA, MDAI and MDMA. Ethylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These are the neurotransmitters17 KB (2,532 words) - 22:27, 31 July 2022
- schres.2013.12.018. ISSN 0920-9964. 3-HO-PCP (Tripsit) | https://wiki.tripsit.me/wiki/3-HO-PCP https://www.zakonyprolidi.cz/cs/2013-463?text=o+sezname20 KB (2,510 words) - 17:29, 17 March 2024
- the 5-HT2A and 5-HT2B receptors. It has also been speculated that 5-APB acts as a releasing agent for the previously mentioned neurotransmitters. This means it effectively14 KB (2,336 words) - 23:43, 21 April 2024
- http://www.drugs.com/international/fentanyl.html Fentanyl: Incapacitating Agent, NIOSH, CDC, 2021 Mutschler, E., ed. (2001). Arzneimittelwirkungen: Lehrbuch21 KB (3,331 words) - 23:49, 21 April 2024
- with MAOIs, RIMAs, SSRIs, stimulants or any substance which acts as a releasing agent or reuptake inhibitor of monoamine neurotransmitters. 5-MeO-DMT is O-demethylated26 KB (3,619 words) - 19:56, 7 April 2024
- research suggests that heating it at 340°C (644°F) unbinds the acetyl group, releasing toxic ketene gas. Chemical conversion: acetic anhydride + Δ-9-THC/Δ-8-THC27 KB (3,598 words) - 22:59, 21 April 2024
- research suggests that heating it at 340°C (644°F) unbinds the acetyl group, releasing toxic ketene gas. Chemical conversion: acetic anhydride + Δ-9-THC/Δ-8-THC65 KB (8,816 words) - 18:09, 27 April 2024
- adrenergic receptors. It also acts as a NDRA (norepinephrine-dopamine releasing agent). Ephedrine, a sympathomimetic amine, acts on part of the sympathetic13 KB (1,767 words) - 16:46, 7 April 2024
- tank or whippet. Releasing the gas into a balloon first allows the gas to warm before being administered. Medical nitrous oxide is released slowly. Hypoxia37 KB (4,981 words) - 01:27, 11 May 2024
- is strongly discouraged. Entactogens - Combining SSRIs with serotonin releasers such as MDMA, mephedrone, and AMT can result in serotonin syndrome. Tramadol15 KB (1,687 words) - 18:59, 22 November 2023
- acuminata - DMT-Nexus Wiki Acacia baileyana Wikipedia | https://en.wikipedia.org/wiki/Acacia_baileyana Acacia baileyana - DMT-Nexus Wiki Acacia burkittii70 KB (630 words) - 04:11, 16 May 2024
- that NM-2-AI most likely acts as both a dopamine and norepinephrine releasing agent. This means it effectively boosts the levels of the norepinephrine and11 KB (1,914 words) - 23:46, 21 April 2024
- Many users claim kratom is useful in treating opioid addiction as a weaning agent, particularly during the initial withdrawal phase.[citation needed] Kratom42 KB (6,087 words) - 13:21, 16 April 2024
- additional methoxy group bonded to the α-methyl group. Mexedrone acts as a releasing agent of serotonin and a reuptake inhibitor for monoamine neurotransmitters10 KB (1,757 words) - 23:45, 21 April 2024
- much less prevalent and intense than those that occur with serotonin releasing agents such as MDMA. Seizure[citation needed] - This is a rarely observed30 KB (4,417 words) - 23:36, 21 April 2024
- component is however much less common and intense than it is with serotonin releasing agents such as MDMA. Seizure[citation needed] - This is a rare effect but67 KB (8,112 words) - 22:04, 6 May 2024
- constituent. Methiopropamine functions as a selective norepinephrine-dopamine releasing agent. This allows dopamine and norepinephrine to accumulate within the brain13 KB (2,010 words) - 00:43, 1 August 2022
- tolerance. Users taking hallucinogenic doses should have a hypertensive agent available or a supervisor present. Exercise extreme caution when attempting14 KB (2,302 words) - 04:47, 22 January 2024
- much less prevalent and intense than those that occur with serotonin releasing agents such as MDMA. Seizure[citation needed] - Psychedelics are known to24 KB (3,279 words) - 18:46, 12 November 2022
- Propylhexedrine affects the central nervous system (CNS) by acting as a releasing agent for the monoamine neurotransmitters dopamine, norepinephrine, and serotonin20 KB (2,813 words) - 21:23, 25 October 2023
- monkeys, without the adverse effects associated with older dopamine releasing agent (e.g., amphetamine).[citation needed] Despite this, ethcathinone may17 KB (2,584 words) - 12:23, 5 April 2024
- substituted cathinones, which display both reuptake-inhibition and releasing agent properties, pentedrone has been shown to act as a pure reuptake inhibitor17 KB (2,503 words) - 00:26, 6 May 2024
- Sames, D. (15 July 2014). "The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist". Translational Psychiatry. 4:20 KB (2,399 words) - 00:17, 6 May 2024
- pharmaceutical company Boehringer Ingelheim in 1964 as a potential anorexigenic agent. The patent describes its synthesis together with other derivatives of aminoketone25 KB (3,455 words) - 23:45, 21 April 2024
- drugs such as MAOIs, RIMAs, stimulants and any substance which act as a releasing agent or reuptake inhibitor of neurotransmitters such as serotonin and dopamine22 KB (2,938 words) - 21:31, 14 November 2023
- decrease sleepiness are not fully understood, evidence suggests that these agents promote wakefulness by acting directly or indirectly on many components18 KB (3,163 words) - 18:25, 30 April 2024
- reducing pain, causing sleepiness, and feelings of pleasure. They can be released in response to pain, strenuous exercise, orgasm, or general excitement20 KB (3,051 words) - 14:51, 16 April 2024
- methamphetamine, desomorphine made this way is often contaminated with various agents. The street name in Russia for homemade desomorphine is krokodil (Russian:24 KB (3,013 words) - 22:01, 27 July 2022
- reputation or escrow system. Trusted members of the community may act as escrow agents. Centralized Markets. The original "Silkroad" was the first of this kind7 KB (481 words) - 04:15, 30 January 2023
- List of articles (category PsychonautWiki)spray guide Staggering guide Edit Agonist Antagonist Reuptake inhibitor Releasing agent Inverse agonist Positive allosteric modulator Negative allosteric modulator502 bytes (5,908 words) - 20:25, 10 June 2017