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using our guidelines.   The Subjective Effect Index (SEI) is a collection of wiki articles designed to serve as a comprehensive reference work for the diverse

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comparable to that of Tramadol though it mechanism is largely unknown. Wakefulness - Thebaine is often consumed alongside other opiate alkaloids in the form

suppression Thought deceleration Wakefulness }} Aleksandr Voskresensky. (n.d.). [Photograph]. Https://En.Wikipedia.Org/Wiki/Aleksandr_Voskresensky. Cocoa

darker areas. Scenarios consisting of severe sleep deprivation caused by wakefulness can lead to more intense visual effects and even hallucinations. Double

This effect manifests and is also intensified at higher doses. Wakefulness - Strong wakefulness is reported at high doses and can last for many hours after

this substantion. It can get up to around 2.5-3 points on the psychonaut wiki scale. (click Traces above to read more) Transformations - This effect occurs

energy levels, datura is commonly considered to be extremely tiring. Wakefulness - Even though datura is a depressant overall and causes sleepiness, it

and hallucinogens. Subjective effects can vary but generally include wakefulness, focus enhancement, appetite suppression, thought acceleration, ego inflation

compressed timescale. SCPs are designed to draw attention to sections of the Wiki that are being actively developed to signal their potential unreliability

noticeably, although not to the same extent as typically reported with MDMA. Wakefulness - This effect is present, but to a noticeably lesser degree than MDMA

how it compares to other substituted and non-substituted amphetamines. Wakefulness Stamina enhancement Thought acceleration Focus enhancement Analysis enhancement

Rejuvenation Thought acceleration Thought connectivity Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Synaesthesia

degree; possibly more than any other commonly used recreational substance. Wakefulness Enhancements Hallucinations Distortions Tinnitus - Tinnitus is rarely

ones. The internal light show began. Consistent with the description on the Wiki. Quickly became very intense internal fractals with digital and neon colours

substance of the xanthine class. Notable effects include stimulation, wakefulness, enhanced focus and motivation. It is the most widely consumed psychoactive

to other effects like analysis enhancement and immersion enhancement. Wakefulness - The administration of DMT with a MAOI can extend the effects for long

Motivation enhancement Memory enhancement Stimulation Anxiety suppression Wakefulness Aniracetam Coluracetam Fasoracetam Nefiracetam Oxiracetam Phenylpiracetam

syndrome Temporary erectile dysfunction Psychosis Anxiety Dream potentiation Wakefulness Amnesia Cognitive fatigue Confusion Decreased libido Delirium Disinhibition

others) is a eugeroic substance of the benzhydryl class that produces wakefulness-promoting and stimulant effects when administered. It is commonly used

Adrafinil (also known as Olmifon) is a prodrug for modafinil - a wakefulness-promoting agent (eugeroic) with nootropic effects. Adrafinil is metabolized

apnea, shift work sleep disorder, and narcolepsy. In addition to its wakefulness-promoting effects and ability to increase locomotor activity in animals

receptor activation and activates predominantly the GHB receptor, leading to wakefulness. Disclaimer: The effects listed below cite the Subjective Effect Index

Memory suppression Ego death Thought acceleration Thought loops Delusion Wakefulness Enhancements Distortions Hallucinations Existential self-realization Perception

records of the preparation of prolintane for use as a mild CNS stimulant, wakefulness agent, and cessation aid for cocaine addiction. It has been marketed in

humor Laughter fits Memory suppression Increased libido Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

Bodily control enhancement Thought acceleration Thought organization Wakefulness Time distortion - This can be described as the experience of time speeding

Thought loops Thought connectivity Time distortion Mindfulness Déjà vu Wakefulness Enhancements Distortions Hallucinations Machinescapes Synaesthesia It

acceleration Immersion enhancement Motivation enhancement Increased libido Wakefulness The effects which occur during the offset of a stimulant experience generally

brain and induces temporary improvements including enhanced alertness, wakefulness, and stimulation.[citation needed] Relative to caffeine, it displays about

lower dosages, GBL is physically stimulating, encouraging movement and wakefulness. At higher dosages, however, it becomes physically sedating, encouraging

is most prevalent at low-moderate doses. Wakefulness - 3,4-CTMP often results in extended periods of wakefulness, especially when redosed. Increased music

usually impair concentration. Thought acceleration Analysis enhancement Wakefulness Memory enhancement Motivation enhancement Euphoria Compulsive redosing

speeding up and passing much quicker than it usually would when sober. Wakefulness Although many report 3-FPM to have minor comedowns, many also report redosing

moderate dosages as anything higher will usually impair concentration. Wakefulness Memory enhancement - Therapeutic doses of methylphenidate improve performance

toward semantic and emotional thought patterns. Wakefulness - 4F-EPH is relatively weak in wakefulness-promoting abilities when compared to methylphenidate

be extremely tiring. Low doses are often used and sold as a sleep aid. Wakefulness - Even though diphenhydramine is primarily a depressant and causes sleepiness

Bodily control enhancement Thought acceleration Thought organization Wakefulness Time distortion - This can be described as the experience of time speeding

acceleration Disinhibition Cognitive euphoria Stimulation Motivation enhancement Wakefulness Novelty enhancement The aftereffects of cocoa powder are usually very

inhibition of histamine, allowing vigilance to increase. As these elements of wakefulness begin to return REM cycles and brief awakenings occur with increasing

it usually would when sober. Thought acceleration Analysis enhancement Wakefulness Motivation enhancement Increased music appreciation The effects which

a mild physical and mental stimulation effect, encouraging movement, wakefulness, and productivity. At common doses and higher, baclofen is physically

Thought acceleration Thought organization or Thought disorganization Wakefulness Time distortion - This can be described as the experience of time speeding

Increased libido Thought acceleration Thought connectivity Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

yawning Watery eyes Pupil dilation Vasoconstriction[citation needed] Wakefulness Teeth grinding - This component is considerably less intense when compared

it makes colours appear more vibrant. Visual haze Anxiety suppression Wakefulness Thought connectivity Focus enhancement Thought acceleration Motivation

yawning Watery eyes Pupil dilation Vasoconstriction[citation needed] Wakefulness Teeth grinding - This component is considerably less intense when compared

enhancement Focus enhancement Thought acceleration Analysis enhancement Wakefulness Memory enhancement Motivation enhancement Euphoria Compulsive redosing

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness The cognitive effects of NM-2-AI can be broken down into several components

suppression Thought deceleration Wakefulness Cognitive euphoria Thought acceleration Focus enhancement Anxiety suppression Wakefulness Analysis enhancement Motivation

Depression Irritability Motivation suppression Thought deceleration Wakefulness Many users of this compound have reported positive, functional cognitive

Increased libido - This effect is one of the most powerful among entactogens. Wakefulness The effects which occur during the offset of a stimulant experience generally

speeding up and passing much quicker than it usually would when sober. Wakefulness - This effect typically only occurs following the use of higher or multiple

yawning Watery eyes Pupil dilation Vasoconstriction[citation needed] Wakefulness Teeth grinding - This component is considerably less intense when compared

death Time distortion Déjà vu Delusion Thought acceleration Thought loops Wakefulness Auditory distortion Auditory enhancement Auditory hallucination Reports

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness The cognitive effects of isopropylphenidate can be broken down into several

Memory suppression Ego death Thought acceleration Thought loops Delusion Wakefulness Enhancements Distortions Hallucinations Existential self-realization Perception

Laughter fits Memory suppression Ego death Increased libido Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

I look in the mirror, my eyes are dry and my pupils are very large." Wakefulness - "No luck in getting to sleep" Emotion enhancement - "I begin to think

itself lucidly, rather than invoking carelessness or dulling thought. Wakefulness Mindfulness Anxiety suppression Thought connectivity Focus enhancement

Bodily control enhancement Thought acceleration Thought organization Wakefulness Time distortion - This can be described as the experience of time speeding

Music may sound more immersive when under the influence of tramadol. Wakefulness Anecdotal reports which describe the effects of this compound within our

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness Empathy, affection, and sociability enhancement Cognitive euphoria Compulsive

experience increase in suicidal and self-harming thoughts and behaviors. Wakefulness Brain zaps Headache Depression Anxiety Irritability Dream potentiation

connectivity Thought loops Time distortion Unity and interconnectedness Wakefulness Brain zaps Enhancements Distortions Hallucinations Anecdotal reports which

increase in the perception of perceived experience is greatly increased Wakefulness Auditory distortion Auditory hallucination Psychosis - This compound may

Suggestibility enhancement Increased sense of humor Laughter fits Mindfulness Wakefulness Enhancements Distortions Hallucinations Existential self-realization Unity

Irritability Motivation suppression Wakefulness Cognitive euphoria Thought acceleration Focus enhancement Anxiety suppression Wakefulness Analysis enhancement Motivation

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness Further information: Research chemicals § Toxicity and harm potential

it usually would when sober. Thought acceleration Thought organization Wakefulness Cognitive euphoria Enhancements Hallucinations - Use of lisdexamfetamine

Mindfulness Thought connectivity Time distortion Unity and interconnectedness Wakefulness Enhancements Distortions Hallucinations There are currently no anecdotal

Motivation enhancement Increased libido Mindfulness Thought acceleration Wakefulness - This component is present, but to a noticeably lesser degree than MDMA

connectivity Thought loops Time distortion Unity and interconnectedness Wakefulness Enhancements Distortions Hallucinations There are currently no anecdotal

readily induce psychosis if it is abused for prolonged periods of time. Wakefulness Auditory distortion Auditory hallucination The effects which occur during

Thought acceleration Thought connectivity Thought loops Time distortion Wakefulness Enhancements Distortions Hallucinations Anecdotal reports which describe

moderate dosages as anything higher will usually impair concentration. Wakefulness Memory enhancement Novelty enhancement Thought acceleration Thought organization

Motivation suppression Thought deceleration Wakefulness - According to anecdotal reports, residual feelings of wakefulness can persist for up to 12 hours after

new to the substance; often with effects like appetite suppression and wakefulness reportedly being less intense with earlier exposures to the drug. Analysis

suppression Ego death Thought acceleration Thought connectivity Time distortion Wakefulness Enhancements Distortions Hallucinations Anecdotal reports which describe

has more of a "stoning" or demotivating effect. Thought acceleration Wakefulness The effects which occur during the offset of a stimulant experience generally

thinking as well as reducing anxiety and depression. Creativity enhancement Wakefulness Mindfulness Anxiety suppression Thought connectivity Focus enhancement

with other stimulants such as amphetamine, cocaine, or methamphetamine. Wakefulness Thought acceleration Thought organization Analysis enhancement Motivation

appreciation Mindfulness Motivation enhancement Thought acceleration Wakefulness - This component is present, but to a noticeably lesser degree than MDMA

suppression Novelty enhancement Personal bias suppression Time distortion Wakefulness Enhancements - MiPT has been reported to notably enhance auditory sensation

Irritability Memory enhancement Motivation enhancement Thought connectivity Wakefulness There are currently no anecdotal reports which describe the effects of

enhancement Bodily control enhancement Stamina enhancement Tactile enhancement Wakefulness Rejuvenation Anxiety suppression Thought connectivity Thought organization

appreciation Memory suppression Ego death Novelty enhancement Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

Users commonly report contradictory effects at higher (>2400mg) doses. Wakefulness Mindfulness Analysis enhancement Thought connectivity Focus enhancement

this compound can be described as a stimulating. Analysis enhancement Wakefulness Mindfulness Anxiety suppression Thought connectivity Focus enhancement

Rejuvenation Thought acceleration Thought connectivity Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination There

dosages, 1,4-Butanediol is physically stimulating, encouraging movement and wakefulness. At higher dosages, however, it becomes physically sedating, encouraging

perceived tunes. Analysis enhancement Ego dissolution Thought acceleration Wakefulness The sensory effects of DiPT are mostly auditory, however it may still

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness The cognitive effects of ETH-CAT can be broken down into several components

appreciation Personal bias suppression Increased libido Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Dosage

Personal bias suppression Thought connectivity Thought loops Time distortion Wakefulness Anecdotal reports indicate that users of 4-AcO-MiPT, as well as 4-HO-MiPT

speeding up and passing much quicker than it usually would when sober. Wakefulness The effects which occur during the offset of a stimulant experience generally

less intense in relation to psilocybin. Thought loops Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

Memory suppression Ego death Immersion enhancement Thought loops Delusion Wakefulness Enhancements Distortions Unity and interconnectedness There are currently

dysphoria, due to all the adverse effects. Dream suppression Time distortion Wakefulness At moderate to high dosages, PMMA is capable of producing typically mild

commonly include: Cognitive fatigue Thought deceleration Anxiety Depression Wakefulness Irritability Anxiety suppression Analysis enhancement Cognitive euphoria

Increased libido Thought acceleration Thought connectivity Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

be overwhelming if the user is having a difficult trip. Sleepiness & *Wakefulness The auditory effects of this combination are extremely consistent in occurrence

a mild physical and mental stimulation effect, encouraging movement, wakefulness, productivity and socialization. At higher doses, however, it becomes

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness Anecdotal reports which describe the effects of this compound within our

Increased music appreciation Motivation enhancement Emotion suppression Wakefulness There are currently no anecdotal reports which describe the effects of

Motivation enhancement Increased libido Mindfulness Thought acceleration Wakefulness Enhancements Hallucinations Distortions Existential self-realization Unity

Personal bias suppression Thought acceleration Thought loops Time distortion Wakefulness Distortions Enhancements Hallucinations Existential self-realization Unity

Dizziness[citation needed] Nausea[citation needed] Focus enhancement Wakefulness Thought acceleration Memory enhancement Motivation enhancement Increased

apparent and is often of a terrifying nature. Time distortion Thought loops Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

acceleration Thought connectivity Thought organization Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia Dosage independent

to easily break down, oftening resulting in smelling similar to fish. Wakefulness - In comparison to citicoline, alpha-GPC manifests itself primarily in

appreciation Personal bias suppression Increased libido Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Dosage

music appreciation Personal bias suppression Memory suppression Ego death Wakefulness Increased libido Visual acuity enhancement Colour enhancement Pattern

Thought acceleration Thought connectivity Thought loops Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Synaesthesia

appreciation Personal bias suppression Increased libido Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Dosage

Motivation suppression Thought deceleration Wakefulness Thought acceleration Analysis enhancement Wakefulness Increased music appreciation Focus enhancement

disorganization Thought loops Time distortion Unity and interconnectedness Wakefulness Enhancements Distortions Hallucinations Anecdotal reports which describe

suppression Thought acceleration Thought connectivity Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Synaesthesia

Memory suppression Ego death Immersion enhancement Thought loops Delusion Wakefulness Enhancements Distortions Hallucinations Unity and interconnectedness There

thought streams Thought disorganization Thought loops Time distortion Wakefulness Synaesthesia - In its fullest manifestation, this is a very rare and non-reproducible

a mild physical and mental stimulation effect, encouraging movement, wakefulness, and productivity. At common doses and higher, phenibut is physically

Motivation enhancement Rejuvenation Thought connectivity Thought organization Wakefulness There are currently no anecdotal reports which describe the effects of

overshadowed by euphoric stimulation. Compulsive redosing Time distortion Wakefulness The effects which occur during the offset of a stimulant experience generally

Colour enhancement Auditory enhancement Mindfulness Tactile enhancement Wakefulness Anxiety suppression Thought connectivity Focus enhancement Immersion enhancement

enhancement Memory enhancement Motivation enhancement Cognitive euphoria Wakefulness Increased music appreciation - It appears less consistently and the effect

music appreciation Personal bias suppression Memory suppression Ego death Wakefulness Increased libido Enhancements Distortions Hallucinations Anecdotal reports

suppression Thought acceleration Thought connectivity Time distortion Wakefulness - Due to it's relaxing nature, some users report being able to sleep after

Thought connectivity Thought loops Confusion Delusion Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Synaesthesia

and is often of a terrifying nature. Increased libido Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucination Synaesthesia

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness There are currently no anecdotal reports which describe the effects of

suppression Novelty enhancement Thought acceleration Time distortion Wakefulness Enhancements Distortions Hallucinations The effects which occur during

Thought acceleration Thought connectivity Thought loops Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucinations Spirituality

enhancement - Citicoline may prevent and treat eye damage related to glaucoma. Wakefulness - In comparison to Alpha-GPC, Citicoline manifests itself primarily in

death Time distortion Déjà vu Delusion Thought acceleration Thought loops Wakefulness Auditory distortion Auditory enhancement Auditory hallucination Synaesthesia

Thought acceleration Thought connectivity Mindfulness Time distortion Wakefulness Enhancements Distortions Hallucinations Spirituality enhancement Unity

meaning enhancement Thought acceleration Thought loops Time distortion Wakefulness Enhancements Distortions Hallucinations Spirituality enhancement Perception

Thought acceleration Thought disorganization Thought loops Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucinations Synaesthesia

Thought acceleration Thought disorganization Thought loops Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucinations Synaesthesia

suppression Thought acceleration Thought connectivity Time distortion Wakefulness Enhancements Distortions Hallucinations There are currently no anecdotal

death Time distortion Déjà vu Delusion Thought acceleration Thought loops Wakefulness Auditory distortion Auditory enhancement Auditory hallucination Synaesthesia

intensification Insomnia Memory enhancement Mindfulness Motivation enhancement Wakefulness - In comparison to citicoline, meclofenoxate manifests itself primarily

suppression Thought acceleration Thought connectivity Time distortion Wakefulness Enhancements Distortions Hallucinations There are currently no anecdotal

effect is consistent in its manifestation and introspection dominant. Wakefulness - This effect is due to its powerful stimulant and hallucinogenic effects

dysphoria, due to all the adverse effects. Dream suppression Time distortion Wakefulness At moderate to high dosages, PMA is capable of producing typically mild

death Time distortion Déjà vu Delusion Thought acceleration Thought loops Wakefulness Auditory distortion Auditory enhancement Auditory hallucination Reports

influence. Memory suppression Ego death Thought loops Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

reports suggest it can be especially likely to occur with this compound. Wakefulness Auditory effects are reported to be more pronounced with ETH-LAD than

Rejuvenation Autonomous voice communication Thought connectivity Time distortion Wakefulness Enhancements Distortions Hallucinations Note: For a number of individuals

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness There are currently no anecdotal reports which describe the effects of

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness There are currently no anecdotal reports which describe the effects of

Thought acceleration Thought disorganization Thought loops Time distortion Wakefulness Enhancements Distortions Hallucinations Synaesthesia - In its fullest

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness Further information: Research chemicals § Toxicity and harm potential

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness Anecdotal reports which describe the effects of this compound within our

Thought acceleration Thought disorganization Thought loops Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucinations Synaesthesia

its glutamatergic effects. Motivation enhancement Cognitive euphoria Wakefulness Increased music appreciation Mania - This effect only rarely presents

fatigue Depression Irritability Motivation suppression Thought deceleration Wakefulness It should be noted that many users of this substance report it has relatively

whereas moderate doses can actually lead to feelings of stimulation and wakefulness. On very high amounts, however, chances of the individual becoming unconscious

Additional effects of the second plateau can include but are not limited to: wakefulness, physical euphoria, spatial disorientation, perception of bodily lightness

Thought acceleration Thought disorganization Thought loops Time distortion Wakefulness Auditory enhancement Auditory distortion Auditory hallucinations Synaesthesia

substances. Memory enhancement Motivation enhancement Thought acceleration Wakefulness Anecdotal reports which describe the effects of this compound within our

deceleration Novelty enhancement Panic attack Dream potentiation Rejuvenation Wakefulness or Sleepiness Addiction suppression Auditory enhancement Sounds and voices

to be energetic and stimulating, promoting alertness, motivation, and wakefulness in low to moderate doses. Note that the effects vary across all strains

heartbeat Nausea - Some users reported nausea on extremely high doses. Wakefulness Appetite suppression Studies shows that cake is highly addictive due to

of time slowing down and passing much slower than it does while sober. Wakefulness - Users report that it is difficult or impossible to go to sleep for up

meaning intensification Suggestibility intensification Thought acceleration Wakefulness Addiction suppression Anxiety suppression Disinhibition Dream suppression