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• 4-FA
  info - Home  https://psychonautwiki.org/wiki/File:Behandeling-4-fa-intoxicatie.pdf https://psychonautwiki.org/wiki/File:4-FA%20risicobeoordeling%20(2016)
  21 KB (3,439 words) - 15:42, 30 July 2022
• PCP
  been characterized as a potent D2 dopamine agonist but not a dopamine reuptake inhibitor in humans. This D2 dopamine agonism contributes to the infamous
  25 KB (3,130 words) - 14:33, 16 April 2024
• Amphetamine
  species and autoxidation of dopamine. In rodents and primates, sufficiently high doses of amphetamine causes damage to dopamine neurons, characterized as
  41 KB (5,610 words) - 19:01, 7 April 2024
• Molecular structure
  In order to maintain consistency across the wiki, images of molecular structures should be produced in a standardized format rather than obtained from
  19 KB (857 words) - 09:55, 15 September 2022
• Research chemicals
  other MAOIs, stimulants and certain substances which release serotonin or dopamine. It is recommended to avoid blends or branded products if the active psychoactive
  19 KB (2,209 words) - 23:08, 21 April 2024
• 3-MeO-PCE
  1371/journal.pone.0194984. ISSN 1932-6203.  3-MeO-PCE (TripSit) | https://wiki.tripsit.me/wiki/3-MeO-PCE https://www.zakonyprolidi.cz/cs/2013-463?text=o+seznam
  20 KB (2,787 words) - 17:34, 17 March 2024
• Methamphetamine
  to excessive pre-synaptic dopamine autoxidation, a mechanism of neurotoxicity. Similar to the neurotoxic effects on the dopamine system, methamphetamine
  41 KB (5,798 words) - 13:29, 16 April 2024
• Content Style Guide - Substance
  the wiki. For example adding two brackets around a term like "serotonergic psychedelic" (serotonergic psychedelic) will link to the PsychonautWiki page
  10 KB (1,405 words) - 18:40, 20 August 2020
• Main Page (section Please don't crawl the wiki. Use our API instead.PsychonautWiki ❤️ Developers. Please report any obstacles.)
  pyrrolidine ⋅ Tropane alkaloid ⋅ Tryptamine Acetylcholine ⋅ Adrenaline ⋅ Dopamine ⋅ GABA ⋅ Glutamate ⋅ Hormone ⋅ Melatonin ⋅ Neuron ⋅ Neurotransmitter ⋅
  21 KB (1,004 words) - 23:38, 13 May 2024
• PCE
  (PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M
  18 KB (2,543 words) - 21:36, 21 July 2022
• 4-FMA
  pharmacology, but it likely produces its effects by increasing levels of dopamine, norepinephrine, and serotonin in the brain. 4-FMA was first detected being
  21 KB (3,467 words) - 16:14, 30 July 2022
• 25I-NBOMe
  ISSN 0378-4274.  https://psychonautwiki.org/wiki/File:Nbome_death_news_i2013e0190_disp.jpg https://psychonautwiki.org/wiki/File:Nbome_death_news_i2013e0191_disp
  28 KB (4,417 words) - 14:00, 16 April 2024
• MDPV
  primarily as a potent norepinephrine-dopamine reuptake inhibitor. Reduced re-uptake of norepinephrine and dopamine results in higher concentrations of the
  23 KB (3,267 words) - 23:45, 21 April 2024
• MDMA
  and 6-APB. It produces its effects by promoting the release of serotonin, dopamine, and norepinephrine in the brain, particularly serotonin. MDMA was first
  85 KB (10,499 words) - 14:24, 16 April 2024
• Substituted piperazines
  stimulant effects. Responsible use Dopamine Substituted piperidine [Piperazine (Wikipedia)https://en.wikipedia.org/wiki/Piperazine] Substituted piperazine
  5 KB (298 words) - 10:10, 24 May 2022
• 6-APB
  serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) with Ki values of 117, 150, and 2698 nM for the norepinephrine transporter (NET), dopamine transporter
  33 KB (4,870 words) - 14:34, 16 April 2024
• Dissociatives
  cognitive and memory impairment and amnesia. Some dissociatives affect the dopamine and/or opioid systems and are capable of inducing euphoria. Dissociatives
  12 KB (1,097 words) - 02:41, 12 May 2024
• Stimulants
  prominent of which are increasing concentrations of the neurotransmitters dopamine and norepinephrine by either promoting release (e.g. amphetamine, methamphetamine)
  11 KB (1,055 words) - 02:52, 12 May 2024
• 3-MeO-PCP
  PCP-Thread-%28Part-1%29 3-MeO-PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential Morris, H., Wallach
  25 KB (3,520 words) - 21:44, 6 May 2024
• Antidepressants (section Norepinephrine and dopamine reuptake inhibitors (NDRIs))
  thought to work by increasing levels of certain neurotransmitters, such as dopamine, serotonin, and/or norepinephrine in certain regions in the brain. MAOIs
  9 KB (1,069 words) - 21:47, 13 May 2024
• 2C-B
  experienced by users of 2C-B. Research also suggests that 2C-B increases dopamine levels in the brains of rats which may contribute to its psychoactivity
  36 KB (4,745 words) - 16:35, 7 April 2024
• Methylphenidate
  primarily acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). It is most active at modulating levels of dopamine and, to a lesser extent, norepinephrine
  31 KB (4,254 words) - 15:15, 6 May 2024
• Opioids
  receptors with serotonin, dopamine, and norepinephrine. Activation of mu receptors allows for the disinhibition of serotonin and dopamine neurons by blocking
  19 KB (2,797 words) - 02:47, 12 May 2024
• Cocaine
  and thus dopamine accumulates in the synaptic cleft. The increased concentration of dopamine in the synapse activates post-synaptic dopamine receptors
  47 KB (6,322 words) - 08:08, 3 May 2024
• Mephedrone
  reinforcing potential of mephedrone. Dopamine and serotonin were collected using microdialysis, and increases in dopamine and serotonin were measured. Mephedrone
  29 KB (3,963 words) - 14:23, 16 April 2024
• 2-FMA
  acts as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine and dopamine in the brain
  17 KB (2,934 words) - 17:24, 18 January 2024
• 2-FA
  primarily as both a dopamine and norepinephrine releasing agent. This means it effectively increases the levels of the norepinephrine and dopamine neurotransmitters
  17 KB (3,024 words) - 17:25, 18 January 2024
• MDA
  with MDMA, MDA is thought to act primarily as a serotonin-norepinephrine-dopamine reuptake inhibitor and releasing agent.[citation needed] However, MDA is
  31 KB (4,379 words) - 12:23, 6 May 2024
• Adrenaline
  monoamine chain can be found in many neurotransmitters, including histamine, dopamine, serotonin and noradrenaline. It is also found in many psychoactive substances
  5 KB (628 words) - 23:12, 21 April 2024
• Lisdexamfetamine
  such as dopamine, serotonin and noradrenaline. The agonism of this set of receptors results in the release of increased concentrations of dopamine, serotonin
  23 KB (3,617 words) - 09:16, 17 April 2024
• Modafinil
  not reduced by the dopamine receptor antagonist haloperidol in rats. In addition, alpha-methyl-p-tyrosine, an inhibitor of dopamine synthesis, blocks the
  19 KB (3,104 words) - 11:29, 16 April 2024
• Isopropylphenidate
  widely-prescribed ADHD medication methylphenidate. It is a norepinephrine-dopamine reuptake inhibitor (NDRI). Isopropylphenidate has been investigated for
  19 KB (2,684 words) - 18:04, 30 July 2022
• 3-FPM
  1950s. It produces its activity by increasing the levels of serotonin, dopamine, and norepinephrine in the brain. The synthesis and pharmacology of 3-FPM
  15 KB (2,265 words) - 06:42, 8 September 2023
• 3-MMC
  of mephedrone (4-MMC). The mechanism of action is not fully studied, but dopamine and serotonin and norepinephrine releasing activity is known to be involved
  18 KB (2,590 words) - 21:20, 30 April 2024
• 4F-MPH
  thought to act primarily as a dopamine and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of dopamine and norepinephrine neurotransmitters
  16 KB (2,465 words) - 15:45, 9 May 2024
• ΑMT
  releasing agent of the main three monoamines; serotonin, norepinephrine, and dopamine, and as a non-selective serotonin receptor agonist. αMT's psychedelic effects
  25 KB (2,825 words) - 16:14, 28 November 2022
• 3-FEA
  potent dopamine releaser. This indicates that 3-FEA effectively increases the levels of all the three major monoamine neurotransmitters dopamine, norepinephrine
  19 KB (3,317 words) - 15:23, 30 July 2022
• GHB
  profile of GHB. GHB's effect on dopamine release is biphasic. This means that while low concentrations stimulate dopamine release via the GHB receptor, higher
  35 KB (4,460 words) - 13:32, 16 April 2024
• 3-FA
  the notable exception of 4-FA), it most likely acts primarily as both a dopamine and norepinephrine releasing agent, with modest selectivity for serotonin
  15 KB (2,726 words) - 11:39, 17 February 2024
• MDAI
  highly selective serotonin releasing agent (SSRA) with neglible effects on dopamine and norepinephrine. MDAI was developed by the American medicinal chemist
  17 KB (2,560 words) - 07:40, 12 October 2023
• 1V-LSD
  known, but it is likely similar to that of LSD, which acts on serotonin, dopamine, and norepinephrine receptors in the brain. 1V-LSD is a research chemical
  28 KB (3,658 words) - 15:27, 10 March 2023
• Ethylphenidate
  both a dopamine reuptake inhibitor and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters
  18 KB (2,561 words) - 14:02, 16 April 2024
• A-PVP
  includes compounds like MDPV, hexen, and a-PHP. It acts as a norepinephrine-dopamine reuptake inhibitor. α-PVP was patented in the 1960s by Boehringer Ingelheim
  24 KB (3,456 words) - 00:08, 3 November 2023
• 2-Aminoindane
  acts as both a dopamine and norepinephrine releasing agent. This means it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters
  12 KB (1,928 words) - 23:42, 21 April 2024
• Methylone
  mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. These neurotransmitters are thought to be responsible for regulating pleasure
  19 KB (2,841 words) - 14:21, 16 April 2024
• Risperidone
  is as a D2 dopaminergic receptor antagonist. This means that it blocks dopamine from binding to the receptor, meanwhile not activating it.[citation needed]
  4 KB (510 words) - 11:41, 22 June 2023
• Desoxypipradrol
  stimulants, increases dopamine levels in the brain which can lead to severe manic psychosis in the short-term in addition to persisting dopamine receptor down
  19 KB (2,776 words) - 00:39, 1 August 2022
• Cyclazodone
  such as dopamine, serotonin and noradrenaline. The agonism of this set of receptors results in the release of increased concentrations of dopamine, serotonin
  19 KB (2,675 words) - 16:54, 31 March 2024
• Memantine
  effects of chronic memantine treatment. Memantine acts as an agonist at the dopamine D2 receptor with equal or slightly higher affinity than to the NMDA receptors
  17 KB (2,270 words) - 05:20, 1 May 2024
• Selective serotonin reuptake inhibitor
  sertraline has noticeable activity at the dopamine transporter protein and could be considered a serotonin-dopamine reuptake inhibitor. Several other SSRIs
  15 KB (1,687 words) - 18:59, 22 November 2023

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