Search results

comprehensive {{citation needed|reason=Your explanation here|date=September 2023}} clause. Example: 65% of people believe machine elves are real.[citation needed]

dangerous and often fatal overdoses that have surfaced over the years.[citation needed] In a comparison of 25x-NBOMe and 2C-x chemicals, each 25x-NBOMe molecule

in Poland.[citation needed] Slovak Republic: Beginning March 1, 2011, 4-Fluoroamphetamine is controlled in the Slovak Republic.[citation needed] Switzerland:

in April 2016.[citation needed] The addition of 5-HTP can greatly increase the effects of 25i-NBOME and should be avoided.[citation needed] It is strongly

found to occur in the human body, although their function is unclear.[citation needed] Most of the known substituted tryptamines act as psychedelics (e.g

of human use prior to being sold online as a designer drug in 2010.[citation needed] Extremely little is known about the pharmacological properties, metabolism

suggest, ...,"[citation needed] "..., has been reported,"[citation needed] "Based on reports, it is likely that, ..., "[citation needed] Prefer short alternatives

25C-NBOMe, all which produce strong experiences at doses above 1mg.[citation needed] Compounds of the NBOMe family are not orally active and should be administered

(PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M

hallucination High blood pressure[citation needed] Increased bodily temperature[citation needed] Increased heart rate[citation needed] Increased perspiration Motor

pressure[citation needed] Increased bodily temperature[citation needed] Increased heart rate[citation needed] Increased perspiration Dehydration[citation needed]

suggests that it may have a higher affinity for dopamine or serotonin.[citation needed] Disclaimer: The effects listed below cite the Subjective Effect Index

history of human use before being sold online as a designer drug in 2010.[citation needed] Subjective effects include stimulation, open and closed-eye visuals

substance.[citation needed] France: DMT is classified as a narcotic.[citation needed] Hungary: DMT is illegal to possess, produce and sell.[citation needed] Germany:

Schedule I (class A) in New Zealand.[citation needed] Poland - PCE is Schedule II (II-P group) in Poland.[citation needed] Portugal - Effective July 2001,

been reported to be highly dose-dependent and variable in its effects.[citation needed] It is unknown whether the studied opioid properties in animal models

death ☠. Abnormal heartbeat[citation needed] Appetite suppression Bodily control enhancement Bronchodilation[citation needed] Dehydration -- It is advised

nystagmus. Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed] Increased perspiration Dehydration

Vasoconstriction Dehydration[citation needed] Increased perspiration[citation needed] Increased bodily temperature Increased heart rate[citation needed] Temporary erectile

Georgia, Louisiana, Mississippi, Texas,[citation needed] South Carolina and Virginia, Indiana, and Ohio[citation needed]. Arizona: In 2018, The State Of Arizona

Stimulation Stamina enhancement[citation needed] Abnormal heartbeat[citation needed] Increased heart rate[citation needed] - Higher doses of MDPV can create

most addictive substances due to the intense euphoria it produces.[citation needed] Additionally, unlike amphetamine at therapeutic doses, methamphetamine

affinity for inhibiting the relatively unstudied PCP2 glutamate receptor.[citation needed] Although 3-MeO-PCP was once claimed to possess opioid or dopaminergic

even when taken at the seemingly same dose in an unpredictable manner.[citation needed] This may contribute to the relative risk it is poses compared to most

Österreich).[citation needed] Canada: Lorazepam is listed in Schedule IV of the Controlled Drugs and Substances Act in Canada.[citation needed] China: Lorazepam

Psychotropic Substances of 1971.[citation needed] Australia: Flunitrazepam is a Schedule 8 (S8) or controlled drug.[citation needed] Austria: Flunitrazepam is

cognitive and affective processing, psychomotor functioning, anesthesia.[citation needed] There is ongoing speculation as to whether this compound possesses

already well-rested.[citation needed] Appetite suppression[citation needed] Bronchodilation - Theobromine is a bronchodilator.[citation needed] Dizziness - This

taking 40mg d-AMP. Appetite suppression Bronchodilation Dehydration[citation needed] Dry mouth Frequent urination Difficulty urinating Increased bodily

obesity.[citation needed] They have also gained widespread illicit use as recreational substances, despite the efforts of various governments.[citation needed]

safeguarding the information needed to make informed decisions about exploring one's body and consciousness PsychonautWiki is an open content platform whose

extension For Chrome For Firefox Citation depository Purdue OWL APA Formatting and Style Guide CiteFast APA citation generator

resemble morphine or other opiates in their pharmacological effects.[citation needed] Opioids work by binding to opioid receptors, which are found in the

of 2005.[citation needed] Austria: 2C-T-2 is illegal to possess, produce and sell under the SMG (Suchtmittelgesetz Österreich).[citation needed] Belgium:

Class C.[citation needed] Nigeria: It is a crime to be seen with cocaine.[citation needed] Pakistan: Use and possession of cocaine is illegal.[citation needed]

potential.[citation needed] Chronic use is associated with escalating tolerance and psychological dependence in some individuals.[citation needed] It has

improving the brain's oxygen supply, or by stimulating nerve growth.[citation needed] The word nootropic was coined in 1972 by a Romanian psychologist and

use laws.[citation needed] British Virgin Isles: The sale of mushrooms is illegal, but possession and consumption is legal.[citation needed] Bulgaria:

Nausea[citation needed] Pupil constriction[citation needed] Decreased libido[citation needed] Appetite suppression Orgasm suppression[citation needed] Seizure[citation

and addiction.[citation needed] Additionally, chronic use is associated with negative effects on the brain and other organs.[citation needed] There is also

conditions via hydrolysis,[citation needed] which is how it becomes metabolically active in the human body as well.[citation needed] In terms of its physical

barbiturates.[citation needed] Tolerance will develop to the sedative-hypnotic, anxiolytic, and euphoric effects of barbiturates after prolonged use.[citation needed]

central histamine H1 receptor.[citation needed] The peripheral inverse agonism induces the allergy reducing effects.[citation needed] Like many first-generation

withdrawal.[citation needed] Abrupt discontinuation also causes rebound stimulation which presents as anxiety, insomnia and restlessness.[citation needed] If one

glands and certain neurons in humans and animals.[clarification needed][citation needed] Adrenaline is used to regulate heart rate, blood vessel and air

heart in high doses.[citation needed] Aspirin: Aspirin overdose starts below 300mg/kg and can become deadly at 500mg/kg.[citation needed] Higher doses of aspirin

psychedelics (e.g. 2C-x, DOx, or 25x-NBOMe) that are typically more dangerous.[citation needed] It is highly advised to use harm reduction practices if using this

1cP-MiPLA trips. Temperature regulation suppression[citation needed] Increased bodily temperature[citation needed] Nausea Stamina enhancement - Generally mild

well as in the venom of a single toad species (Incilius alvarius).[citation needed] Although little is known about its history, it is believed to have

in Australia.[citation needed] Austria: LSA containing seeds are not regulated, thus are legal to possess, produce and sell.[citation needed] Germany: LSA

suppression Muscle contractions Increased heart rate[citation needed] Increased blood pressure[citation needed] Increased perspiration Nausea - Mild to extreme

Zealand.[citation needed] Norway: Ketamine is a Class A drug in Norway.[citation needed] Singapore: Ketamine is a Class A drug in Singapore.[citation needed]

prominent around stairs and slopes. Respiratory depression[citation needed] Dizziness[citation needed] - Dizziness is sometimes present with higher doses, although

suppression Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed] Increased perspiration Muscle

nutmeg.[citation needed] Additionally, myristicin is the traditional precursor for the psychedelic and empathogenic drug MMDA.[citation needed] Nutmeg

the second most predominant alkaloid in opium (up to three percent).[citation needed] Although codeine can be extracted from natural sources, a semi-synthetic

possess and sell in Belgium.[citation needed] Croatia: Salvinorin A is illegal to possess and sell in Croatia.[citation needed] Czech Republic: Salvinorin

Österreich).[citation needed] Australia: GHB, 1,4-B and GBL are all Class B illegal drugs, along with any possible esters, ethers and aldehydes.[citation needed]

overdose include anything from organ failure to cardiac arrest and death[citation needed]. There are also multiple reports of people lethally injuring themselves

its appearance on the online research chemical market in the 2010s.[citation needed] Subjective effects include geometric visual effects, time distortion

metabolism, and toxicity of 3-MMC, and it has little history of human use.[citation needed] Preliminary evidence suggests chronic use (i.e. high dose, repeat administration)

neurotransmitter serotonin, eventually leading to improved mood.[citation needed][clarification needed] SSRIs can be dangerous when used in combination with other

equivalent to 1.66 grams of the sodium salt of GHB (Sodium oxybate).[citation needed] GBL is a common solvent and reagent in chemistry and is also used as

neurotransmitters serotonin, dopamine, and norepinephrine in the brain.[citation needed] Mephedrone was first synthesized in 1929, but did not become widely

available through a prescription.[citation needed] Russia: Promethazine is available through a prescription.[citation needed] United States: Promethazine is

temperature Abnormal heartbeat[citation needed] Increased blood pressure[citation needed] Increased heart rate[citation needed] Dehydration Diarrhea Difficulty

documented in 2006 by a team at Purdue University led by David Nichols.[citation needed] It has been studied in its 11C radiolabelled form as a potential ligand

duration of the experience. Increased blood pressure[citation needed] Increased heart rate[citation needed] Appetite suppression Increased perspiration Muscle

streets in northern Switzerland under the name "Acomet" or "Azomet".[citation needed] Very little data exists about the pharmacological properties, metabolism

higher doses. Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed] Increased perspiration Temperature

Temperature regulation suppression Increased heart rate[citation needed] Increased blood pressure[citation needed] Muscle contractions Muscle spasms Muscle cramps

substances—it is eaten in parts of Europe, Asia, and North America.[citation needed] Amanita muscaria has been used as an intoxicant and entheogen by the

heart rate[citation needed] Increased blood pressure[citation needed] Temperature regulation suppression Increased bodily temperature[citation needed] Increased

(prescription-only medicine).[citation needed] United States: Memantine is only available through a prescription.[citation needed] Responsible use Hallucinogen

Österreich).[citation needed] Brazil: Heroin is listed as a controlled substance, making the production, distribution, or possession illegal.[citation needed] Canada:

been reported to be highly dose-dependent and variable in its effects.[citation needed] It is said to produce little stimulating effects compared to 3-MeO-PCP

(FDA) in 1955 for treating what was then known as "hyperactivity."[citation needed] Although it was prescribed to patients as early as 1960, it only became

explored as a potential stimulant nootropic in the 1-8mg dosage range.[citation needed] Little data exists about the pharmacological properties, metabolism

itself as the peak sets in. Increased blood pressure[citation needed] Increased heart rate[citation needed] Increased perspiration Muscle contractions Muscle

4-HO-MPT. It has been sold online as a research chemical as of 2016.[citation needed] It was synthesised and described by Alexander Shulgin in his 1994 book

sleep,[citation needed] this is a trait currently unique to Gaboxadol and some related GABAergics such as pregabalin[citation needed], GHB[citation needed]

blood pressure[citation needed] Increased heart rate[citation needed] Muscle contractions Muscle spasms Vasoconstriction[citation needed] - This effect

prescription only and unscheduled.[citation needed] France: It is available by prescription only and unscheduled.[citation needed] Germany: Quetiapine is a prescription

human use before being sold online as a research chemical in 2016.[citation needed] It remains obscure and is either used recreationally or for research

within China's borders has forced production to nations worldwide.[citation needed] Subjective effects such as euphoria, thought acceleration, disinhibition

history of human use before being sold online as a designer drug in 2011.[citation needed] It is closely related to members of the 25x-NBOMe series, which have

itself as the peak sets in. Increased blood pressure[citation needed] Increased heart rate[citation needed] Increased perspiration Muscle contractions Muscle

itself as the peak sets in. Increased blood pressure[citation needed] Increased heart rate[citation needed] Increased perspiration Muscle contractions Muscle

Zolpidem can increase heart rate.[citation needed] Increased blood pressure - Zolpidem can increase blood pressure.[citation needed] Tactile hallucination Visual

was patented as an anorectic under the trade name "Amphedoxamine".[citation needed] Contemporary reports suggest that MDA emerged as a recreational drug

affect it more so than LSD. Increased blood pressure[citation needed] Increased heart rate[citation needed] Increased perspiration Muscle contractions Muscle

suppression Muscle contractions Increased heart rate[citation needed] Increased blood pressure[citation needed] Increased perspiration Nausea - Mild to extreme

Österreich) as an analogue of LSD.[citation needed] Germany: 1cP-AL-LAD is illegal in Germany as of July 2021.[citation needed] Switzerland: 1cP-AL-LAD can be

active dose. This suggests that it is well-tolerated physiologically.[citation needed] Today, 4-HO-MiPT is either used recreationally or as an entheogenic

opioids, it has few biological effects, notably a lower pain threshold.[citation needed] Naloxone has two isomers, (+)naloxone and (-)naloxone, with the latter

such as being dehydrated, undernourished, overheated, or fatigued.[citation needed] Visual acuity enhancement Colour enhancement Pattern recognition enhancement

5-HT2C serotonin receptors.[citation needed] Risperidone has the strongest affinity to the 5-HT2A receptor.[citation needed] On top of that, it acts as

Article 76 of the Schengen Treaty.[citation needed] Belgium: Hydrocodone is no longer available for medical use.[citation needed] Canada: Hydrocodone is a Schedule

Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed] Headaches[citation needed] Stomach bloating

"Temple of True Inner Light". More experienced members ingest a DPT tea.[citation needed] Very little data exists about the pharmacological properties, metabolism

although it may prolong the experience and exacerbate side effects.[citation needed] Codeine (3-methylmorphine) is a prodrug for morphine. While codeine

on-going debate as to whether they possess their own innate activity.[citation needed] There is very little information on the human pharmacology or toxicity

history of human use before being sold online as a designer drug in 2011.[citation needed] It is closely related to members of the 25x-NBOMe series, which have

'hyped' for a long time but was on hold due to synthesis difficulties.[citation needed] HXE or 2-(Ethylamino)-2-(3-hydroxyphenyl)cyclohexan-1-one is classed

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

available via prescription only.[citation needed] Canada: The drug is available via prescription only.[citation needed] Germany: Haloperidol is a prescription

requires a prescription.[citation needed] Turkey: Mirtazapine is classed as anti-depressant so it is prescription only drug[citation needed] but the law is often

brain.[citation needed] MiPLA was first discovered by Albert Hoffman as a part of the original structure-activity research for LSD.[citation needed] It has

methylphenidate in animal studies[citation needed], but likely has weaker reinforcing effects due to its slower onset of action.[citation needed] According to anecdotal

Bodily control enhancement Increased heart rate[citation needed] Increased blood pressure[citation needed] Temperature regulation suppression Muscle relaxation

tryptamines, phenethylamines and lysergamides. Increased heart rate[citation needed] Olfactory hallucination Pupil dilation Increased salivation Excessive

"legal highs" products.[citation needed] It has been mass produced in China and sold online as a research chemical.[citation needed] It has been linked to

"associated with a long tradition of historical cultures worldwide."[citation needed] Leeds Metropolitan University is currently the only university in the

psychological dependence which may bring significant harm to the user.[citation needed] It is highly advised to use harm reduction practices if using this

various foods and drinks containing products derived from the kola nut.[citation needed] Unlike many other psychoactive drugs, caffeine is legal and unregulated

rectally).[citation needed] Notably, it is reported to produce significantly less euphoria in comparison to other opioids.[citation needed] Dextropropoxyphene

relatively short-lived balance of entactogenic and stimulant effects.[citation needed] Based on related compounds, it is not unreasonable to speculate that

or sell MXE. Russia: It is illegal to possess, produce, or sell MXE.[citation needed] Slovenia: MXE is a controlled substance (Official Gazette of RS No

temperature Abnormal heartbeat[citation needed] Increased blood pressure[citation needed] Increased heart rate[citation needed] Dehydration Diarrhea Difficulty

euphoria Tactile enhancement Increased heart rate[citation needed] Increased blood pressure[citation needed] Nausea Excessive yawning Pupil dilation There

relaxation[citation needed] - Bromazolam is reported to produce moderate muscle relaxation greater than that of alcohol. Motor control loss[citation needed] -

value.[citation needed] Austria: Methaqualone is illegal to possess, produce and sell under the SMG (Suchtmittelgesetz Österreich).[citation needed] Canada:

heart rate[citation needed] Increased perspiration Increased blood pressure[citation needed] Temperature regulation suppression[citation needed] Increased

just with its own stylistic pharmacodynamic and kinetic variations.[citation needed] MPT is extremely uncommon and has little history of human usage. It

pharmacologist David E. Nichols during the 1990s at Purdue University.[citation needed] in the 2010s, MDAI was marketed alongside novel entactogens like 5-MAPB

Spontaneous physical sensations Increased heart rate[citation needed] Increased blood pressure[citation needed] Nausea Pupil dilation Colour enhancement Pattern

Giurgea and other scientists at the Belgian pharmaceutical company UCB.[citation needed] In the United Kingdom, piracetam is prescribed mainly for myoclonus

network of online research chemical vendors during the early 2000s.[citation needed] Very little data exists about the pharmacological properties, metabolism

also called (+)-D-PRO-LAD, has an absolute configuration of (5R, 8R).[citation needed] It is a structural analog of lysergic acid, with an N,N-diethylamide

discussion as to whether they might display their own intrinsic activity.[citation needed] Like with most psychedelic tryptamines, 4-AcO-DET is thought to act

pure) heroin and roughly 80 to 100 times more potent than morphine.[citation needed] A wide range of pharmaceutical fentanyl preparations are available

intensely when compared to amphetamine or cocaine. Increased heart rate[citation needed] Appetite suppression - The above components are also accompanied by

5-HT2A partial agonist, through which it exerts its psychedelic effects.[citation needed] However, the role of these interactions and how they result in the

DPH inhibits the metabolism of DXM and increases its concentration,[citation needed] DXM in turn suppresses the perceived dysphoric and anxiogenic effects

Norway.[citation needed] Switzerland: Zopiclone is listed as a "Abgabekategorie B" pharmaceutical, which generally requires a prescription.[citation needed]

Clonazepam is Schedule H in India.[citation needed] Israel: Clonazepam is available by prescription only.[citation needed] New Zeland: Clonazepam is a Schedule

Spontaneous physical sensations Increased heart rate[citation needed] Increased blood pressure[citation needed] Nausea Pupil dilation Colour enhancement Pattern

has been reached. Abnormal heartbeat[citation needed] Increased heart rate Increased blood pressure[citation needed] Appetite suppression - This effect

such as being dehydrated, undernourished, overheated, or fatigued.[citation needed] The visuals of 3C-E are generally not that apparent and consist more

about the pharmacological properties, metabolism, and toxicity of EPT.[citation needed] It is highly advised to use harm reduction practices if using this

(PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M

numbing Excessive yawning Watery eyes Pupil dilation Vasoconstriction[citation needed] Wakefulness Teeth grinding - This component is considerably less intense

nitrous oxide is a powerful oxidizer similar to molecular oxygen.[citation needed] At room temperature, nitrous is a colorless and non-flammable gas with

blood pressure[citation needed] - This effect is typically present at the higher doses.[citation needed] Increased heart rate[citation needed] - This effect

receptor subtypes with similar potency.[citation needed] Clonidine also has peripheral α1 agonist activity.[citation needed] Clonidine is also an agonist for

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

tobacco smoking, which include heart disease and various forms of cancer.[citation needed] While the link between tobacco use and cancer is well-established,

Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed] Headaches[citation needed] Dehydration Stomach

gabapentinoids (such as phenibut), baclofen has stronger dizziness. Dehydration[citation needed] Headaches Pupil dilation Appetite enhancement Frequent urination Difficulty

edema. Dihydrocodeine is available in suppository form on prescription.[citation needed] Dihydrocodeine is used as an alternative or adjunct to codeine and

Increased bodily temperature Increased heart rate[citation needed] Increased blood pressure[citation needed] Nausea - Mild to extreme nausea is consistently

The original synthesis of diphenidine was first reported in 1924.[citation needed] However, it was not selected for further development. Shortly after

receptors of the body. CBD accounts for up to 41% of the plant's extract.[citation needed] Cannabis produces CBD-carboxylic acid through the same metabolic pathway

in certain individuals.[citation needed] Increased heart rate[citation needed] Dizziness[citation needed] Nausea[citation needed] Focus enhancement Wakefulness

GABAergic activity.[citation needed] As the GABA system is the most prevalent inhibitory receptor set within the brain[citation needed], its modulation may

and alprazolam (Xanax). Diazepam is considered to have low toxicity.[citation needed] However, it has moderate abuse potential and produces physical and

omberacetam develops over several weeks of prolonged and repeated use.[citation needed] This results in users having to administer increasingly larger doses

putative entheogen. It has no documentation of being sold on the streets[citation needed] and is almost exclusively obtainable as an obscure gray area research

name "Benzofury" before its sale and import were subsequently banned.[citation needed] Compared to other members of its family such as 6-APB and 5-MAPB, this

system with prolonged use. Increased heart rate[citation needed] Increased blood pressure[citation needed] Teeth grinding Focus enhancement - This component

perspiration Dehydration Frequent urination Dry mouth Vasoconstriction[citation needed] Increased libido - 3-FPM is known for having aphrodisiac properties

appeared for sale on the online research chemical market in the 2010s.[citation needed] Subjective effects are similar to mescaline and include open and closed-eye

enhancement Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed] Appetite suppression Bronchodilation

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

daytime sleepiness.[citation needed] The long-term risks of regular armodafinil intake have yet to be studied in detail.[citation needed] Armodafinil, or

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

Dehydration[citation needed] Vasoconstriction[citation needed] Increased blood pressure[citation needed] Muscle relaxation[citation needed] Tactile enhancement

numbing Excessive yawning Watery eyes Pupil dilation Vasoconstriction[citation needed] Wakefulness Teeth grinding - This component is considerably less intense

(Neue-Psychoaktive-Substanzen-Gesetz Österreich).[citation needed] Belarus: This substance was banned on January 1, 2010.[citation needed] Brazil: Possession, production

effects at the GABAB receptor are responsible for its sedating effects.[citation needed] Recent research has shown that phenibut binds to and blocks α2δ subunit-containing

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

typical doses. Stamina enhancement Abnormal heartbeat[citation needed] Increased heart rate[citation needed] - Cyclazodone is reported to elevate heart rate

decrease as the dose increases.[citation needed] Physical euphoria - This is reported to be present even at low doses.[citation needed] Spatial disorientation

slip and fall when walking down slopes or stairs. Seizure suppression[citation needed] - Gabapentin is commonly used as an anticonvulsant. It is often combined

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

how tofu absorbs the flavors of sauces or spices it is cooked with.[citation needed] While some use this as evidence that 2C-D is relatively uninteresting

chemical substitutes for classical street stimulants and entactogens.[citation needed] Of these, 2-FA is considered to be most amphetamine-like in its subjective

cause brain damage, and has an extremely low toxicity relative to dose.[citation needed] There are relatively few physical side effects associated with acute

substance.[citation needed] Japan: Butylone is a controlled substance.[citation needed] Norway: Butylone is a controlled substance.[citation needed] Poland:

purchase as a dietary supplement.[citation needed] Italy: Melatonin is legal to purchase as a dietary supplement.[citation needed] Ireland: Melatonin is a prescription-only

Increased heart rate[citation needed] Increased blood pressure[citation needed] Increased perspiration Pain relief[citation needed] Teeth grinding - This

stimulation.[citation needed] Relative to caffeine, it displays about 2/3rds the potency in terms of the stimulation it produces.[citation needed] The mechanisms

0°C or below, but slowly degrades at normal room temperature (25°C).[citation needed] Further information: Serotonergic psychedelic According to various

of memory, this could potentially account for its nootropic effects.[citation needed] Trimethylamine (betaine) production. Trimethylamine is necessary for

thought to underlie their toxicity (specifically alpha-methyl-dopamine).[citation needed] Although it is likely to be physically safe to try in a responsible

validated.[citation needed] Tactile enhancement Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed]

temperature (which is the major cause of death in PMMA mortalities).[citation needed] Disclaimer: The effects listed below cite the Subjective Effect Index

it is has been approved for and is commonly sold as a sleeping pill.[citation needed] While "Z-drugs" were initially thought to have less misuse potential

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

duration. It is insoluble in water, but dissolves in ethanol and lipids.[citation needed] Unlike cannabis, the chronic abuse of synthetic cannabinoids has been

enhancement Abnormal heartbeat[citation needed] Increased heart rate[citation needed] Increased blood pressure[citation needed] Appetite suppression Bronchodilation

substance.[citation needed] Russia: mCPP is a controlled substance.[citation needed] Sweden: mCPP is a controlled substance.[citation needed] Switzerland:

preserve reactions in the body as a form of metabolic 'maintenance'.[citation needed] SAM-e is available over the counter and by prescription in the treatment

is 36% more potent by mass so doses should be adjusted accordingly.[citation needed] 5-(2-methylaminopropyl)benzofuran, or 5-MAPB, is a substituted benzofuran

maintenance, and creation of PsychonautWiki content. Need help getting started? Please see the official MediaWiki help page for information on editing content

reached. Tactile enhancement Increased heart rate[citation needed] Increased blood pressure[citation needed] Temperature regulation suppression Pupil dilation

withdrawal.[citation needed] Abrupt discontinuation also causes rebound stimulation which presents as anxiety, insomnia and restlessness.[citation needed] If one

to be capable of causing psychological dependence among most users.[citation needed] Tolerance to many of the effects of adrafinil develops with prolonged

researched psychedelic substances. The pharmacology of LAE-32 is complex[citation needed], but it acts primarily by binding to serotonin receptors in the brain

Hungary in 2013. Japan: AMT is illegal to possess, produce and sell.[citation needed] Latvia: AMT is a Schedule I drug. Lithuania: As of 2012, AMT is controlled

counterparts. (S)-Propylhexedrine can be synthesized from methamphetamine.[citation needed] Freebase propylhexedrine is nonpolar, volatile, oily liquid at room

Controlled Drugs and Substances Act, so it is technically not illegal.[citation needed] Germany: Methallylescaline is controlled under the NpSG (New Psychoactive

in 1998.[citation needed] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health

withdrawal.[citation needed] Abrupt discontinuation also causes rebound stimulation which presents as anxiety, insomnia and restlessness.[citation needed] If one

autonomy by safeguarding the information needed to make informed decisions over one's body and mind PsychonautWiki is an open content platform, meaning anyone

studies, it has a potency of approximately ten times that of diazepam.[citation needed] Its potency has not been systematically tested in humans, but its closest

United Kingdom: MDEA is a Class A drug.[citation needed] United States: MDEA is a Schedule I drug.[citation needed] Responsible use Entactogen Stimulant

a weaning agent, particularly during the initial withdrawal phase.[citation needed] Kratom exists in a variety of strains with different characteristics

doses, can produce muscle spasms.[citation needed] Anecdotally, seizures have been reported in overdose.[citation needed] Respiratory depression - While

is available with the advice of a pharmacist without a prescription.[citation needed] United Kingdom: The drug is available over the counter as a pharmacy

antagonist, although other neurotransmitter systems may be involved.[citation needed] NMDA receptors (a subtype of receptors for glutamate, which are the

itself as the peak sets in. Increased blood pressure[citation needed] Increased heart rate[citation needed] Increased perspiration Muscle contractions Muscle

substance).[citation needed] Canada: Schedule I.[citation needed] Germany: Anlage II (Authorized trade only, not prescriptible).[citation needed] United States:

insomnia, acute seizures, and the sedation of hospitalized patients.[citation needed] However, it is currently exclusively sold by online research chemical

Spontaneous physical sensations Increased heart rate[citation needed] Increased blood pressure[citation needed] Nausea Dry mouth Pupil dilation Teeth grinding

Temazepam is listed in Schedule 4, making it a prescription only medicine.[citation needed] Austria: Temazepam is legal for medical use under the AMG (Arzneimittelgesetz

methylnaphthidate is believed to act as a monoamine reuptake inhibitor.[citation needed] However, it has been reported to display distinct differences in its

without a prescription under the SMG (Suchtmittelgesetz Österreich).[citation needed] Canada: Buprenorphine is a schedule I substance in Canada and is only

animal studies have shown dopamine levels quickly return to baseline.[citation needed] Tyrosine is a non-essential phenylalanine-derived amino acid. Tyrosine's

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

without a prescription under the SMG (Suchtmittelgesetz Österreich).[citation needed] Canada: Oxycodone is a controlled substance under Schedule I of the

It is half as potent and has a 60% longer half-life than etizolam.[citation needed] This compound was patented in 1995 by a Japanese company as a medication

Temporary erectile dysfunction Increased heart rate[citation needed] Increased blood pressure[citation needed] The visual effects of phenethylamine only occur

kilograms and 12,400 pills of acetylfentanyl (equal to 117,400 doses).[citation needed] As a μ-opioid receptor agonist, acetylfentanyl may serve as a direct

recreationally. Chlordiazepoxide is considered to have low toxicity.[citation needed] It has moderate abuse potential, given its long duration of action

25B:157-162. Lista över hallucinogena växter, svampar och djur - Magiska Molekylers Wiki (in Swedish)  Stafford, G. I., Pedersen, M. E., Staden, J. van, Jäger, A

and/or it is a very vague statement.) grams per kilogram of body weight.[citation needed] Because cocoa can act as a powerful (compared to other weaker stimulants

Practice. Harper & Collins, 2nd edition. 2008. pp. 42–51.Template:Full citation needed Hagan IG, Burney K (July–August 2007). "Radiology of recreational drug

bromine and methyl groups are typically stronger than those without.[citation needed] 4F-MPH is thought to act primarily as a dopamine and norepinephrine

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

interaction may also result in an elevated risk of mania and psychosis.[citation needed] Tramadol - Tramadol is well-documented to lower the seizure threshold

activated neurons without significantly affecting basal levels of dopamine.[citation needed] This could account for its improvements in spatial short-term memory

without a prescription under the SMG (Suchtmittelgesetz Österreich).[citation needed] Germany: Hydromorphone is a controlled substance under Anlage III of

enhancement Teeth grinding Increased blood pressure[citation needed] Increased heart rate[citation needed] Temperature regulation suppression Increased bodily

that suggests that combining these two increases their neurotoxicity.[citation needed] Anecdotally, worsened comedowns are also commonly reported when these

possess, produce and sell under the SMG (Suchtmittelgesetz Österreich).[citation needed] Germany: TMA-2 is controlled under Anlage I BtMG (Narcotics Act, Schedule

insomnia, acute seizures, and the sedation of hospitalized patients.[citation needed] However, it is currently exclusively sold by online research chemical

in the U.S., making it illegal to possess, manufacture, or import.[citation needed] Responsible use Volumetric liquid dosing Research chemical 2C-x 2C-T-2

APA formatted reference Please see the citation formatting guide if you need assistance properly formatting citations. "Ephedrine". The American Society of

manic undertones. Spontaneous physical sensations Increased heart rate[citation needed] - Early reports suggest that the effects of desoxypipradrol on heart

threshold has been reached. Canada - Cinolazepam is not approved for sale[citation needed] United Kingdom - It is illegal to produce, supply, or import this drug

controlled substance. Finland: Methiopropamine is illegal in Finland.[citation needed] Germany: Methiopropamine is controlled under Anlage I BtMG (Narcotics

serotonin syndrome than other serotonergic opioids such as tramadol.[citation needed] Combinations with the following substances can cause dangerously high

be lacking or needing urgent attention over an extended or compressed timescale. SCPs are designed to draw attention to sections of the Wiki that are being

sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).[citation needed] China: 2-AI is a controlled substance. Germany: 2-AI is controlled

trauma and stress.[citation needed] Delta waves are associated with deep sleep cycles and the release of physical awareness.[citation needed] Theta waves are

It can be promoted by redosing multiple times. Appetite suppression[citation needed] Although these effects are not universal, certain people may experience

radically different (though this has yet to be scientifically validated).[citation needed] It is strongly recommended that one use harm reduction practices when

hard to predict independent of any previous benzodiazepine tolerance.[citation needed] Muscle relaxation - Reportedly stronger than Alprazolam. Physical euphoria

"Abgabekategorie B" pharmaceutical, which generally requires a prescription.[citation needed] Citicoline Choline Nootropic Galantamine (Wikipedia) Galantamine (Isomer

ibogaine. Ibogaine also has activity as an NMDA receptor antagonist.[citation needed] Disclaimer: The effects listed below cite the Subjective Effect Index

use of ayahuasca for therapeutic purposes ("vegetalismo") is legal.[citation needed] United States: Louisiana: Except for ornamental purposes, growing,

mg of ethylmorphine and 10 mg of codeine are sold over the counter.[citation needed] Germany: Ethylmorphine is controlled under BtMG Anlage II, making it

inducing effects. Kava replaces alcohol in many Pacific communities.[citation needed] Kava cultures are the religious and cultural traditions of western

TAAR1 receptor.[citation needed] The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors

Schedule I or II, but only if it is intended for human consumption.[citation needed] Responsible use Designer drug Stimulants Substituted amphetamine 2-FA

Sedation[citation needed] - Flubrotizolam can produce very strong sedation effects in moderate to high doses. Appetite enhancement[citation needed] - There

control loss Respiratory depression Increased libido Seizure suppression[citation needed] Appetite enhancement - This effect is not particularly prominent, but

developed in 1959 at the French National Scientific Research Center.[citation needed] Meclofenoxate has been tested as alzheimers treatment. Additionally

morphine. Psychedelics - Methadone is known to lower the seizure threshold[citation needed] and psychedelics may act as triggers for seizures in those who are

specifically named under Verzeichnis D. United Kingdom: PMA is a Class A drug.[citation needed] United States: PMA is a Schedule I substance. Responsible use Substituted

reference Please see the citation formatting guide if you need assistance properly formatting citations. APA formatted citation.

sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).[citation needed] Brazil: Possession, production and sale is illegal as it is listed

or MDMA, thus putting it under the scope of the Federal Analog Act.[citation needed] Responsible use Research chemical Substituted cathinone Entactogen

it is legal to possess without any sort of license or prescription.[citation needed] Germany: Tianeptine is a prescription medicine, according to Anlage

to manufacture, buy, possess, or distribute without a DEA license.[citation needed] Responsible use Volumetric liquid dosing Safer injection guide Sharing

reference Please see the citation formatting guide if you need assistance properly formatting citations. APA formatted citation. AMP Citrate: The New Craze

N-ethylhexedrone to be caustic to the nasal membrane when it is insufflated.[citation needed] A toxicology screening indicated that measured with yeast and SH-SY5Y

appended to Portaria SVS/MS nº 344. China: NEP is a controlled substance.[citation needed] Germany: NEP is controlled under the NpSG (New Psychoactive Substances

main psychoactive compound in cake. It's a ç1 and ç2 partial agonist.[citation needed] Disclaimer: The effects listed below cite the Subjective Effect Index

reference Please see the citation formatting guide if you need assistance properly formatting citations. APA formatted citation.

APA formatted reference Please see the citation formatting guide if you need assistance properly formatting citations. 依托咪酯持续输注在临床中的应用, additional text. Abuse

later in another day. Please see the citation formatting guide if you need assistance properly formatting citations.

APA formatted reference Please see the citation formatting guide if you need assistance properly formatting citations.

APA formatted reference Please see the citation formatting guide if you need assistance properly formatting citations.