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using psychoactive substances. The first section covers general harm reduction practices for all substance classes while the latter is specific to hallucinogens

extensive content collection covering the scientific research and harm reduction practices relevant to hallucinogen and general psychoactive substance experimentation

history of human usage. It is strongly recommended that one use harm reduction practices if using this substance. 3-MeO-PCE, or N-Ethyl-1-(3-methoxyphe

(PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M

toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. 4-Fluoroamphetamine (4-FA) is

psychedelic substance with the proper amount of precaution and harm reduction practices when using it. 25D-NBOMe, or 2C-D-NBOMe, is a serotonergic N-benzyl

toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. 3-HO-PCP was first synthesized

be overly difficult to use safely. It is highly advised to use harm reduction practices if using this substance. 25C-NBOMe or 2C-C-NBOMe is a serotonergic

psychedelic substance with the proper amount of precaution and harm reduction practices if using it. 25N-NBOMe or 2C-N-NBOMe is a serotonergic N-benzyl

arylcyclohexylamines, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. On October 18, 2012 the Advisory

difficult to use safely. Therefore it is highly advised to use harm reduction practices if using this substance. 25B-NBOMe or 2C-B-NBOMe is a serotonergic

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pressure and increased risk of stroke. It is highly advised to use harm reduction practices if using this substance. Amphetamine was first synthesized in Germany

more severe health risks than others. It is highly advised to use harm reduction practices if using these substances. Popular herb blends include K2 and Spice

elevated risk of stroke and heart attack. It is highly advised to use harm reduction practices if using this substance. Amphetamine was first synthesized in 1887

effects and lack of research, it is strongly advised to use use harm reduction practices if using this substance. 3-Methoxyphencyclidine, or 3-MeO-PCP,

those predisposed to mental disorders. It is highly advised to use harm reduction practices if using this substance. 2C-B was first synthesized and tested

delayed orgasm (see subjective effects). It is highly advised to use harm reduction practices if using this substance. MDMA was first synthesized in 1912 by

those predisposed to mental disorders. It is highly advised to use harm reduction practices if using this substance. DMT was first synthesized in 1931 by the

(PsychonautWiki) | https://psychonautwiki.org/wiki/3-MeO-PCP#Toxicity_and_harm_potential PCP Psychosis (PsychonautWiki) | https://psychonautwiki.org/wiki/3-M

toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. Flags (or tags) are templates

one avoid using datura altogether. Otherwise, extreme caution and harm reduction practices should be used, such as having a sober and prepared trip sitter

reported by nine European countries. It is highly advised to use harm reduction practices if using this substance. MDPV, or 3,4-Methylenedioxypyrovalerone

by online research chemical vendors. It is highly advised to use harm reduction practices if using this substance. The synthesis of 6-APB was first reported

abuse and addiction potential, it is highly advised to use proper harm reduction practices if using this substance.[citation needed] Etizolam first appeared

damage to the brain and other organs. It is highly advised to use harm reduction practices if using this substance. 4-Fluoromethamphetamine (4-FMA) is a synthetic

avoided.[citation needed] It is strongly recommended that one use harm reduction practices when using this substance. 25I-NBOMe is not habit-forming and the

toxic or carcinogenic. It is strongly recommended that one use harm reduction practices when using these drugs. Please be aware that pre-mixed, branded

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this substance. Lorazepam is extremely physically and

to strychnine poisoning. It is strongly recommended that one use harm reduction practices when using this substance. Thebaine is considered of low abuse

repeat the experience due to its unpleasant nature. Please use harm reduction practices if using this substance (e.g. starting with a low dose and always

individual properties of each chemical. It is strongly advised to use harm reduction practices when using these substances. Stimulants may be divided into different

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this drug. The oral LD50 (lethal dose in 50% of the

predisposed to mental disorders. As a result, it is highly advised to use harm reduction practices if using these substances. The term "psychedelic" was coined by

effects, toxicity and harm potential. They can therefore be treated similarly in the appropriate efforts necessary to maximize harm reduction. The median lethal

hallucinogenic substance with the proper amount of precaution and harm reduction practices if using it. Following the initial positive results found by Shulgin's

substances are strongly advised against. It is highly advised to use harm reduction practices if using this substance. Tramadol was synthesized in 1962 by chemists

repeat the experience due to its unpleasant nature. Please use harm reduction practices if using this substance (e.g. starting with a low dose and always

only a brief history of human usage. It is highly advised to use harm reduction practices if using this substance. 3C-P or 3,5-Dimethoxy-4-propoxyamphetamine

limited history of non-medical human use. It is highly advised to use harm reduction practices if using this substance. αMT, or α-Methyltryptamine is a synthetic

has a limited history of human use. It is highly advised to use harm reduction practices if using this substance. Methoxetamine, or (RS)2-(3-methoxyphe

tolerance, and psychological dependence. It is highly advised to use harm reduction practices if using this substance. Methylphenidate was first licensed by

has a limited history of human usage. It is highly advised to use harm reduction practices if using this substance. Methylone, or 3,4-methylenedioxy-N-methylcathinone

typically more dangerous.[citation needed] It is highly advised to use harm reduction practices if using this substance. The ritual use of the Peyote cactus has

already experienced with hallucinogens. It is highly advised to use harm reduction practices if using this substance. 2C-E was first synthesized and tested

(an abbreviated form of 2C-I-NBOMe). It is highly advised to use harm reduction practices if using this substance. 2C-I, or 2,5-dimethoxy-4-iodophenethylamine

individuals (see this section for more). It is highly advised to use harm reduction practices if using this substance. Cocaine is among one of the oldest recreational

hallucinogenic substance with the proper amount of precaution, and harm reduction practices if one chooses to use it. A 1000-year-old collection of drug paraphernalia

Barbiturates have been largely replaced by benzodiazepines in routine medical practice, generally because benzodiazepines have lower toxicity compared to barbiturates

hallucinogenic substance with the proper amount of precaution and harm reduction practices if using it. 1cP-MiPLA, or 1-Cyclopropionyl-N-methyl-N-isopropyllysergamide

tremors, and in severe cases, seizures. It is highly advised to use harm reduction practices if using this substance. Baclofen was synthesized in 1962 by Heinrich

sold as a research chemical online. It is highly advised to use harm reduction practices if using this substance. 4-AcO-MET or 4-Acetoxy-N-methyl-N-ethyltryptamine

is sometimes used for this purpose. It is highly advised to use harm reduction practices if using this substance. Promethazine was developed in the mid-1940s

toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. 3-Cl-PCP was first synthesized

has a limited history of human use. It is highly advised to use harm reduction practices if using this substance. HXE first appeared for sale on the online

profile. When using this substance it is highly advised to use harm reduction practices. 25E-NBOH was first introduced to the scientific community in 2010

relatively short history of human usage. It is highly advised to use harm reduction practices if using this substance. It was first synthesized and studied through

myristicin, as this is extremely uncommon. It is highly advised to use harm reduction practices if using this substance. Myristicin, also known as 3-methoxy,4

benzodiazepines, opioids). As a result, it is highly advised to use harm reduction practices if using this substance. "Social drinking", also commonly referred

provide accurate information of its risks and harm. It is strongly recommended that one use harm reduction practices when using this substance. As with other

documented history of human usage. It is highly advised to use harm reduction practices if using this substance. 4-AcO-DET, or 4-Acetoxy-N.N-diethyltryptamine

history of human usage. It is strongly recommended that one use harm reduction practices if choosing to use this substance. Deschloroketamine, or 2-Phe

hyperalgesia or even revert it. It is strongly recommended that one use harm reduction practices when using this class of substances. Due to the highly euphoric

high abuse potential. As a result, it is highly advised to use harm reduction practices if using this substance. The synthesis of diphenidine was first

extremely brief history of human use. It is strongly advised to use harm reduction practices if using this substance. 2-Fluorodeschloroketamine, or 2-(2-Fl

to psychiatric disorders. It is therefore highly advised to use harm reduction practices if using this substance. LSA, or d-lysergic acid amide, is an organic

psychedelic substance with the proper amount of precaution and harm reduction practices when using it. DPT, or N,N-dipropyltryptamine, is a synthetic indole

enhancement Auditory enhancement It is strongly recommended that one use harm reduction practices when using this substance. The range of possible lethal dosage

DPT) and trained in their safe use. It is highly advised to use harm reduction practices if using this substance. 5-MeO-DMT or 5-methoxy-N,N-dimethyltryptamine

metabolism, and toxicity of 2-FMA. It is strongly advised to use harm reduction practices if using this substance. 2-Fluoromethamphetamine (2-FMA) is a synthetic

those predisposed to mental illness. It is highly advised to use harm reduction practices if using this substance. Psilocin and its phosphorylated inactive

but there is no data to support this. It is highly advised to use harm reduction practices if using this substance. 4-HO-MET, or 4-hydroxy-N-ethyl-N-methyltryptamine

has little history of human usage. It is strongly advised to use harm reduction practices if using this substance. 2C-T-21, or 2,5-dimethoxy-4-ethylfluo

depressants (a somewhat common practice considering its weak effects). It is highly advised to use harm reduction practices if using this substance. Gabapentin

user at risk of oxygen deprivation. It is highly advised to use harm reduction practices if using this substance. Nitrous oxide (also known as laughing

online research chemical market. It is strongly advised to use harm reduction practices if using this substance. 2-Fluoroethamphetamine (2-FEA) is a synthetic

discouraged to take this substance without using the strongest harm reduction practices such as volumetric dosing, limiting intake to oral ingestion, and

chemical testing service before use. It is strongly advised to use harm reduction practices if using this substance. MXiPr first appeared for sale on the online

this novel psychedelic substance with the proper precautions and harm reduction practices if choosing to use it. MET, or N-ethyl-N-methyltryptamine, is a

hyperpolarization of GABAA receptors. It is strongly recommended to use harm reduction practices when using this class of substances. Benzodiazepines are known

no hard data to support this claim. It is highly advised to use harm reduction practices if using this substance. 4-AcO-DMT and several other esters of

sold online as a research chemical. It is highly advised to use harm reduction practices if using this substance. 5-MeO-DiPT, or 5-methoxy-N,N-diisopropyltryptamine

evidence currently exists to support this. It is highly advised to use harm reduction practices if using this substance. 1V-LSD first appeared on the online research

mental disorders (see this section). It is highly advised to use harm reduction practices if using this substance. The original synthesis of LSD was recorded

Due to its habit-forming properties, it is highly advised to use harm reduction practices if using this substance. Phenibut is a derivative of GABA with

has a limited history of human use. It is highly advised to use harm reduction practices if using this substance. 4-HO-DiPT, or 4-Hydroxy-N,N-diisopropyltryptamine

metabolism, and toxicity of allylescaline. It is highly advised to use harm reduction practices if using this substance. Allylescaline, or 4-allyloxy-3,5-dimethoxyphenethylamine

reliable scientific data is lacking. It is highly advised to use harm reduction practices if using this substance. Although formal documentation does not

risks than traditional dissociatives. It is highly advised to use harm reduction practices if using this substance. Ephenidine has been described as a designer

hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it. In a 2007 MAPS newsletter interview, Ann

experienced with using hallucinogens. It is highly advised to use harm reduction practices if using this substance. DOB or 4-Bromo-2,5-dimethoxy-amphetamine

not experienced with hallucinogens. It is highly advised to use harm reduction practices if using this substance. ETH-LAD, or 6-ethyl-6-nor-lysergic acid

has a limited history of human use. It is highly advised to use harm reduction practices if using this substance. DiPT, or N,N-diisopropyltryptamine, is

individuals predisposed to mental disorders. It is highly advised to use harm reduction practices if using this substance. A growing body of evidence suggests that

been documented.[citation needed] It is strongly advised to use harm reduction practices if using this substance. The racemic parent compound of dextromethorphan

lack of information on its properties, it is highly advised to use harm reduction practices if using this substance. 3-Fluorophenmetrazine (3-FPM) is a synthetic

highly experienced with hallucinogens. It is strongly advised to use harm reduction practices if using this substance. These include avoiding "eye-balling" (i

no formal studies that prove this. It is highly advised to use harm reduction practices if using this substance. 1P-LSD first appeared on the online research

this section for more information). It is highly advised to use harm reduction practices if using this substance. Ketamine was first synthesized at Parke

reversible with tapered use and time off. It is highly advised to use harm reduction practices if using this substance. The genus cannabis is indigenous to central

has little history of human usage. It is highly advised to use harm reduction practices if using this substance. Methallylescaline, or 4-methallyloxy-3

psychedelic substance with the proper amount of precaution and harm reduction practices if choosing to use it. DOC was first synthesized by 1972 by Ronald

cardiotoxic properties.[citation needed] It is highly advised to use harm reduction practices if using this substance. Mephedrone, or 4-methylmethcathinone,

risks than traditional dissociatives. It is highly advised to use harm reduction practices if using this substance. Methoxphenidine is an example of a designer

hallucinogenic substance with the proper amount of precaution and harm reduction practices if using it. AL-LAD, or 6-allyl-6-nor-lysergic acid diethylamide

metabolism, and toxicity of 2-FA. It is highly advised to use harm reduction practices if using this substance. 2-FA, or 2-Fluoroamphetamine, is a synthetic

accurate dosing particularly difficult. It is highly advised to use harm reduction practices if using this substance. Diacetylmorphine was originally synthesized

alcohol, opiates, and other depressants. It is highly advised to use harm reduction practices if using this substance. It should be noted that the sudden discontinuation

and toxicity of EPT.[citation needed] It is highly advised to use harm reduction practices if using this substance. EPT, or N-ethyl-N-propyltryptamine, is

hallucinogenic substance with the proper amount of precaution and harm reduction practices if using it. 1cP-AL-LAD, or 1-Cyclopropionyl-6-allyl-6-nor-lysergic

it has little history of human usage. It is highly advised use harm reduction practices if using this substance. PRO-LAD, or 6-propyl-6-nor-lysergic acid

dependence which may bring significant harm to the user.[citation needed] It is highly advised to use harm reduction practices if using this substance. Morphine

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effects and unknown toxicity profile, it is highly advised to use harm reduction practices if using with this substance. α-PVP, or alpha-Pyrrolidinovalerophenone

sold online as a research chemical. It is highly advised to use harm reduction practices when using this substance. 5-MeO-MiPT, or 5-methoxy-N-methyl-N

through online research chemical vendors. It is highly advised to use harm reduction practices if using this substance. α-PHP, or α-Pyrrolidinohexanophenone,

and stimulating nature. It is strongly recommended that one use harm reduction practices if choosing to use this substance. O-PCE, or 2'-Oxo-PCE, belongs

psychedelic substance with the proper amount of precaution and harm reduction practices if using it. DOI was first synthesized by a team at the University

those predisposed to mental illness. It is highly advised to use harm reduction practices if using this substance. LSZ, or d-lysergic acid 2,4-dimethylazetidide

has a limited history of human use. It is highly advised to use harm reduction practices if using this substance. MDAI, or 5,6-methylenedioxy-2-aminoindane

toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. 4F-MPH is a synthetic molecule

of the drug is usually not advised. It is highly advised to use harm reduction practices if using this substance. Zopiclone is a hypnotic nonbenzodiazepine

recreational mirtazapine use is not known. It is highly advised to use harm reduction practices if using this substance. Mirtazapine is a synthetic tetrahedral

toxicity profile, it is strongly recommended that one use proper harm reduction practices if using this substance. 3-FEA, or 3-fluoroethamphetamine, is a

and unknown toxicity profile, it is highly advised that one use harm reduction practices if using this substance. 5-MeO-DiBF, or 5-methoxy-N,N-diisopro

a very short history of human use. It is highly advised to use harm reduction practices if using this substance. The full name of the chemical is N-al

caused by other atypicals. It is strongly recommended that one use harm reduction practices when using this drug. Australia: The drug is available via prescription

toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. 3-FMA, or 3-fluoromethamphetamine

has not been confirmed in studies. It is highly advised to use harm reduction practices if using this substance. Proscaline, or 3,5-dimethoxy-4-propyloxyphenethylamine

hallucinogenic substance with the proper amount of preparation, and harm reduction practices if using it. In 1968 and 1969, a famous batch of LSD known as "Orange

hallucinogenic substance with the proper amount of precaution and harm reduction practices if one chooses to use it. LSM-775, or lysergic acid morpholide

hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it. PARGY-LAD, or 6-propynyl-6-nor-lysergic

toxicity profile, it is strongly recommended that one use proper harm reduction practices if using with this substance. 3,4-CTMP, or 3,4-dichloromethylphenidate

toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance. 4F-EPH, or 4-fluoroethylphenidate

self-harm or serious bodily injury. (see this section for more information).[citation needed] It is highly advised to use harm reduction practices if using

hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it. The original synthesis of βk-2C-B is not

the recommended dosage. As a result, it is highly advised to use harm reduction practices if using this substance. Lisdexamfetamine was developed by New

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. 3C-E is not habit-forming, and the desire

pressure, hospitalization, or (in extreme cases) death. Please use harm reduction practices if using this combination (e.g. starting with low dosages and always

therapy to help tobacco users quit. It is highly advised to use harm reduction practices if using this substance. Crude nicotine was known by 1571, and

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this substance. The acute oral LD50 in rats is 331–2171

metabolism, and toxicity of MiPLA. It is highly advised to use harm reduction practices when using this substance. The chemical name of MiPLA is methy

yet-to-be-discovered toxic properties. It is strongly advised to use harm reduction practices if using this substance. Cyclazodone is a phenyl 4-oxazolidinone

proper precautions, conduct independent research, and use proper harm reduction practices if choosing to use with this substance. The synthesis of 5-APB

recommended that one research this substance's toxicity and use proper harm reduction practices if choosing to use this substance. Dextropropoxyphene is similar

one would drink out of. It is strongly recommended that one use harm reduction practices when using this drug. In multiple studies, GHB has been found to

setting, the safer injection guide should be followed along with all harm reduction practices. Sublingual administration is also considered to be superior to

pharmacology, and toxicity of NM-2-AI. It is highly advised to use harm reduction practices if using this substance. NM-2-AI, or N-methyl-2-AI, is the N-methylated

research on this topic. It is strongly recommended that one use harm reduction practices when using this substance. Responsible use Amanita muscaria Muscimol

metabolism, and toxicity of dichloropane. It is highly advised to use harm reduction practices if using this substance. Dichloropane is a derivative of 3-phenyltropane

dibutylone. Due to the lack of research, it is highly advised to use harm reduction practices if using this substance. Further information: Research chemicals

disinhibited black-out states, it is strongly advised to use proper harm reduction practices if choosing to use this substance. Clonazolam is a drug of the

instead of stopping use abruptly. It is strongly advised to use harm reduction practices if using this substance. Midazolam Hydrochloride is the hydrochloride

of time or in excessive doses. Thorough independent research and harm reduction practices are strongly advised if choosing to use this substance. APICA,

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug. As with other stimulants, the chronic use

only a short history of human use. It is highly advised to use harm reduction practices if using this substance. Methiopropamine, or 1-(thiophen-2-yl)

toxicity of N-ethylhexedrone. Due to this, it is highly advised to use harm reduction practices if using this substance. N-Ethylhexedrone was patented by the German

about its toxicity and abuse potential. It is highly advised to use harm reduction practices if using this substance. (+/-)O-Desmethyltramadol, or 3-(2-((d

administration.[citation needed] It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure

dehydration and nausea. It is strongly recommended that one use harm reduction practices when using this substance. Throughout the world, naloxone is not

and 5x stronger than Alprazolam). It is strongly advised to use harm reduction practices if using this substance. Flualprazolam first appeared on the research

is found when sold on the streets. It is highly advised to use harm reduction practices if using this substance. Dextroamphetamine is the dextrorotary

properties, metabolism, and toxicity. It is highly advised to use harm reduction practices if using this substance. Butylone, or β-keto-N-methylbenzodioxolylbutanamine

literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of

communities are currently lacking. It is highly advised to use harm reduction practices if using this substance. The leaves of M. speciosa contain more

entactogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it. In the United States, MDEA was introduced

g. heroin, morphine, hydrocodone). It is highly advised to use harm reduction practices if using this substance. Tianeptine is a tricyclic antidepressant

adverse drug-drug interactions. As a result, it is advised to use harm reduction practices if using this substance. Cannibidiol was first isolated from Mexican

particularly when it is injected. It is strongly advised to use harm reduction practices if choosing to use this substance. U-47700 is an atypical opioid

cause the same effects. It is strongly recommended that one use harm reduction practices when using this substance. The chronic use of Pramiracetam can

with other depressants. It is strongly recommended that one use harm reduction practices when using this substance. Quaaludes that are sold only for illicit

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. 4-HO-MiPT is not habit-forming, and

substituted cathinone, mephedrone. It is highly advised to use harm reduction practices if using this substance. Ethylcathinone, or ETH-CAT, is a synthetic

began in Estonia in the early 2000s. It is highly advised to use harm reduction practices such as volumetric dosing if choosing to use this substance. Acetylfentanyl

physical and psychological dependence. It is highly advised to use harm reduction practices if using this substance. Propylhexedrine is chemically classified

potentially overwhelming effects, it is strongly recommended that one use harm reduction practices when using this substance. Please see Research Articles below in

novelty and unstudied nature, it is strongly recommended that one use harm reduction practices if experimenting with this substance. As with other stimulants

Experience Vaults: Bromazolam It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances

instead of stopping usage abruptly. It is highly advised to use harm reduction practices if using this substance. Flunitrazolam is a chemical of the benzodiazepine

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance. As with any other GABA receptor agonist

evidence currently exists to support this. It is highly advised to use harm reduction practices if using this substance. 1B-LSD first appeared on the online research

safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug. 4-HO-DPT is not habit-forming, and the desire

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance. F-Phenibut is moderately physically

safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug. As with other NMDA receptor antagonists,

resolve. It is strongly recommended that one use extreme caution and harm reduction practices when using 3-MeO-PCP or PCP. Users should avoid taking the drugs

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. 4-HO-MPT is generally considered not

metabolize caffeine is impaired. It is strongly recommended that one use harm reduction practices when using this substance. Caffeine produces dependence with chronic

causes excess toxicity. It is strongly recommended that one uses harm reduction practices if choosing to use this substance. In February 2002, the European

alkaloids in humans or animals. It is strongly recommended that one use harm reduction practices when using this drug. There is no tolerance built up with harmala

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. 4-HO-EPT is not habit-forming, and the

Experience Vaults: Ephedrine It is strongly recommended that one use harm reduction practices when using this substance. In comparison to other stimulants, ephedrine

with other depressants. It is strongly recommended that one use harm reduction practices when using this substance. The oral LD50 for clonidine in mice

treated with extreme caution. It is highly advised that one use harm reduction practices if choosing to use this substance. Anecdotal evidence shows most

like alcohol or opioids. It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure

as well as the mouth.[1] It is strongly recommended that one use harm reduction practices when using this substance. A 2022 review compared 43 studies on

psychological dependence and addiction. It is highly advised to use harm reduction practices if using this substance. Ketobemidone was first synthesized during

metabolism, pharmacology, and toxicity. It is highly advised to use harm reduction practices if using this substance. Nifoxipam is a drug of the benzodiazepine

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug. High doses of omberacetam (above 20 mg) can

consequences.[citation needed] It is strongly recommended that one use harm reduction practices when using this substance. Theanine is not habit-forming. Tolerance

substances such as MDMA or MDE. It is strongly recommended that one use harm reduction practices when using this substance. As with other stimulants, the chronic

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this substance. The LD50 for rodents has been established

history of psychosis). It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannibanoids, the

research on this topic. It is strongly recommended that one use harm reduction practices when using this substance. Amanita muscaria grows naturally and

treated with extreme caution. It is strongly recommended that one use harm reduction practices if using this substance. Pentedrone is a molecule of the substituted

chemical. Nevertheless, it is strongly recommended that one use harm reduction practices if using this substance. The median lethal dose at which 50% of

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. 4-HO-DET is not habit-forming and the

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this drug. Clonazepam is extremely physically and psychologically

been used in trials to treat opioid addiction trials in which it showed reduction of withdrawal symptoms and addiction. The widespread use of this effect

safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug. Bufotenin is not habit-forming and the desire

Adrafinil, specifically. It is strongly recommended that one use harm reduction practices when using this substance. The chronic use of adrafinil can be

development of lipoid pneumonia. It is strongly recommended that one use harm reduction practices when using this class of substances. There is no real tolerance

commonly used antipsychotics. It is strongly recommended that one use harm reduction practices when using this drug. Compared to other antipsychotics, quetiapine

Regardless, it is strongly recommended that one be familiar with harm reduction practices when using this substance. SAM-e is not habit-forming with a low

understood stimulant substance with the proper amount of precaution and harm reduction practices if choosing to use it. The main structural differences between

physical dependence with continued use. It is strongly advised to use harm reduction practices if using this substance. Pyrazolam was originally developed by

side effects and abuse. It is strongly recommended that one use harm reduction practices when using this drug. Carisoprodol is extremely physically and

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. Escaline is not habit-forming, and the

and an irritated cough. It is strongly recommended that one use harm reduction practices when using this substance. As with other stimulants, the chronic

established at 8100 mg/kg. It is strongly recommended that one use harm reduction practices when using this substance. Unlike other stimulants, bromantane

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance to ensure the administration of the intended

effects of the substance. It is strongly recommended that one use harm reduction practices when using this substance. As with other opioids, the chronic use

Experience Vaults: 25C-NBOH Further information: Research chemicals § Toxicity and harm potential, and Responsible use § Hallucinogens 25C-NBOH is a relatively new

wish to experiment with this compound are advised to use proper harm-reduction practices and approach with this substance with extreme caution (such as

court cases and even death. It is strongly recommended that one use harm reduction practices and have a trip sitter when using this drug. Zolpidem is moderately

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. Although no formal studies have been

a negative experience. It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannibanoids, the

or trouble urinating. It is strongly recommended that one use harm reduction practices when using this drug. As with other antipsychotics, dependence

safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug. 4-AcO-MiPT is not habit-forming and the desire

safe before consumption. It is strongly recommended that one uses harm reduction practices when using this drug. MPT is not habit-forming and the desire to

causes excess toxicity. It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this substances. These include volumetric liquid dosing

safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug. As with many psychedelics, the use of MiPT

Experience Vaults: 25I-NBOH Further information: Research chemicals § Toxicity and harm potential, and Responsible use § Hallucinogens 25I-NBOH is a relatively new

one would drink out of. It is strongly recommended that one use harm reduction practices when using this drug. GBL itself may also produce neurotoxic effects

presumed safety, it is still strongly recommended that one use harm reduction practices when using this drug. The median lethal dosage (LD50) of aniracetam

risks and harm this substance may pose, especially in terms of seriouslong-term health hazards. It is strongly recommended that one use harm reduction practices

Experience Vaults: 25B-NBOH Further information: Research chemicals § Toxicity and harm potential, and Responsible use § Hallucinogens 25B-NBOH is a relatively new

alcohol, opiates, and other depressants. It is highly advised to use harm reduction practices if using this substance. It should be noted that the sudden discontinuation

of 8-10g/kg. Regardless, it is strongly recommended that one use harm reduction practices when using this substance. The median lethal dosage (LD50) of piracetam

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. 1P-ETH-LAD is not habit-forming and

a negative experience. It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannibanoids, the

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this substance. Cinolazepam is extremely physically

alcohol or benzodiazepines. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. DOM is not habit-forming and the desire

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance. As with other stimulants, the chronic

alcohol or benzodiazepines. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug. The median lethal dosage (LD50) of phenylpiracetam

consequences of any sort. It is strongly recommended that one use harm reduction practices when using this substance. Choline is not habit-forming and the

Regardless, it is strongly recommended that one is familiar with harm reduction practices when using creatine. Creatine is not habit-forming with a low potential

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this drug. Flubromazepam is extremely physically and

impure "street" product. It is strongly recommended that one use harm reduction practices when using this drug. As with other opiate-based painkillers, the

effects of opioid agonism. It is strongly recommended that one use harm reduction practices when using this drug. As with other opiate-based painkillers, the

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance. The chronic use of Coluracetam can be

literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug. The median lethal dosage (LD50) of oxiracetam

like alcohol or opioids. It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. Although no formal studies have been

Experience Vaults: mCPP It is strongly recommended that one use harm reduction practices when using this drug. mCPP is not known to be addictive, but there

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this drug. Deschloroetizolam is extremely physically

it is strongly recommended that one is familiar with and uses harm reduction practices when using this substance. Alpha-GPC is not habit-forming and the

Thought deceleration Wakefulness It is recommended that one use harm reduction practices when using this drug. Although cocoa is relatively safe when ingested

potentially cause seizures. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

a negative experience. It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannabinoids, the

safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance. 2C-D is not habit-forming and the desire

like alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this substance. Flubromazolam is extremely physically

potentially cause seizures. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

like alcohol or opioids. It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance. The chronic use of N-methylbisfluoromodafinil

some exist. It is strongly recommended that one be familiar with harm reduction practices when using this drug. Galantamine is not known to be not habit-forming

safe before consumption. It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure

alcohol or benzodiazepines. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

like alcohol or opioids. It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure

fenfluramine and MDMA. It is strongly recommended that one use harm reduction practices when using this drug. As with other entactogenic stimulants, the

a negative experience. It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannibanoids, the

a negative experience. It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannibanoids, the

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug. As with other stimulants, the chronic use

antagonist such as naloxone. It is strongly recommended that one use harm reduction practices when using this drug. As with other opiate-based painkillers, the

a negative experience. It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannabinoids, the

reminiscent of psychedelics such as 4-HO-MET and 2C-B. Tracers Depression reduction Anxiety suppression Cognitive fatigue Focus suppression Dream suppression

sort.[citation needed] It is strongly recommended that one use harm reduction practices when using this drug. As with caffeine, theacrine produces dependence

alcohol or benzodiazepines. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

deter abuse of Suboxone. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

consequences of any sort. It is strongly recommended that one use harm reduction practices when using this substance. Citicoline is not habit-forming and

safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug. 4-AcO-DiPT is not known to be habit-forming

toxic dosage is unknown. It is strongly recommended that one use harm reduction practices when using this drug. Short-term physical health risks of 6-APDB

development of cancer . It is strongly recommended that one use harm reduction practices when using this drug. Pentobarbital is extremely physically and

a negative experience. It is strongly recommended that one use harm reduction practices when using this drug. As with other synthetic cannibanoids, the

Experience Vaults: Tizanidine It is strongly recommended that one use harm reduction practices when using this substance. While no long term studies of tizanidine

development of cancer . It is strongly recommended that one use harm reduction practices when using this drug. Phenobarbital is extremely physically and

development of cancer. It is strongly recommended that one use harm reduction practices when using this drug. Secobarbital is extremely physically and

literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of

doses or after chronic use. It is strongly recommended that one use harm reduction practices when using this drug. Efavirenz is not known to be habit-forming

varying degrees of success. It is strongly recommended that one use harm reduction practices when using this substance. Eszopiclone is extremely physically

fatal serotonin syndrome. It is strongly recommended that one use harm reduction practices when using this drug. As with other opioids, the chronic use of

typical research chemical. It is strongly recommended that one use harm reduction practices when using this substance. The median lethal dose at which 50%

it is strongly recommended that one is familiar with and uses harm reduction practices when using this substance. In vitro studies of meclofenoxate showed

time instead of stopping abruptly. It is highly advised to use harm reduction practices if using this substance. Nitrazepam was developed by Hoffmann-La

any sort. However, it is still strongly recommended that one use harm reduction practices when using this drug. Tyrosine may potentially be mildly habit

Experience Vaults: SUBSTANCE It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances

completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug. As with other stimulants, the chronic use

literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of

benzodiazepines, alcohol or opioids. It is strongly recommended that one use harm reduction practices when using this substance. Pagoclone is extremely physically and

hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it. Experience reports of βOH-2C-B began to

Experience Vaults: SUBSTANCE It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances

original dose, is 4 minutes. It is strongly recommended that one use harm reduction practices when using this substance. As opposed to other stimulants, Semax

literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of

Experience Vaults: SUBSTANCE It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances

Experience Vaults: SUBSTANCE It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances

that if treated with therapy, can result in the reduction of drug use Antidepressants Harm reduction practices Health consequences of drug use Psychiatry.org

alterations in consciousness. It is strongly recommended to follow harm reduction practices and handle consumption responsibly. The legal status of apomorphine

Experience Vaults: SUBSTANCE It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances

Experience Vaults: SUBSTANCE It is strongly recommended that one use harm reduction practices when using this substance. Warning: Many psychoactive substances